Risk Factors for Foot Amputation in Patients Hospitalized for Diabetic Foot Infection
The aim of this study was to identify and quantify risk factors for amputation in diabetic patients hospitalized for foot infections. This cross-sectional study comprised 100 patients with diabetic infectious complications in the lower limbs. The variables investigated were related to diabetes, infe...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Journal of Diabetes Research |
| Online Access: | http://dx.doi.org/10.1155/2016/8931508 |
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| _version_ | 1832559801583796224 |
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| author | Maria Teresa Verrone Quilici Fernando de Sá Del Fiol Alexandre Eduardo Franzin Vieira Maria Inês Toledo |
| author_facet | Maria Teresa Verrone Quilici Fernando de Sá Del Fiol Alexandre Eduardo Franzin Vieira Maria Inês Toledo |
| author_sort | Maria Teresa Verrone Quilici |
| collection | DOAJ |
| description | The aim of this study was to identify and quantify risk factors for amputation in diabetic patients hospitalized for foot infections. This cross-sectional study comprised 100 patients with diabetic infectious complications in the lower limbs. The variables investigated were related to diabetes, infection, and treatment compliance. Multiple Cox regression analysis was performed to identify the variables independently associated with the outcome of amputation. The most prevalent chronic complications were neuropathy and hypertension. Most patients presented with a neuroischemic foot (86%). The Morisky test showed that 72% were not compliant with diabetes treatment. Regarding patient outcome, 61% progressed to amputation, 14% to debridement, and 9% to revascularization. The results showed a 42% higher risk for progression to amputation in patients with previous use of antimicrobials. Also, the amputation risk was 26% higher for those less compliant with diabetes treatment. An increase of one point in the Wagner ulcer classification criteria corresponded to a 65% increase in the risk of amputation. Undergoing conservative, nonsurgical procedures prior to admission provided a 63% reduction in the risk of amputation. Knowledge of these factors is critical to enable multidisciplinary teams to develop treatment plans for these patients so as to prevent the need for amputation. |
| format | Article |
| id | doaj-art-e8f5a9530ec74132834329fa3e739411 |
| institution | Kabale University |
| issn | 2314-6745 2314-6753 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Diabetes Research |
| spelling | doaj-art-e8f5a9530ec74132834329fa3e7394112025-02-03T01:29:12ZengWileyJournal of Diabetes Research2314-67452314-67532016-01-01201610.1155/2016/89315088931508Risk Factors for Foot Amputation in Patients Hospitalized for Diabetic Foot InfectionMaria Teresa Verrone Quilici0Fernando de Sá Del Fiol1Alexandre Eduardo Franzin Vieira2Maria Inês Toledo3Pontifícia Universidade Católica de São Paulo, Sorocaba, SP, BrazilUniversity of Sorocaba, Rodovia Raposo Tavares, Km 92,5, 18023-000 Sorocaba, SP, BrazilPontifícia Universidade Católica de São Paulo, Sorocaba, SP, BrazilUniversidade de Brasília, Brasília, DF, BrazilThe aim of this study was to identify and quantify risk factors for amputation in diabetic patients hospitalized for foot infections. This cross-sectional study comprised 100 patients with diabetic infectious complications in the lower limbs. The variables investigated were related to diabetes, infection, and treatment compliance. Multiple Cox regression analysis was performed to identify the variables independently associated with the outcome of amputation. The most prevalent chronic complications were neuropathy and hypertension. Most patients presented with a neuroischemic foot (86%). The Morisky test showed that 72% were not compliant with diabetes treatment. Regarding patient outcome, 61% progressed to amputation, 14% to debridement, and 9% to revascularization. The results showed a 42% higher risk for progression to amputation in patients with previous use of antimicrobials. Also, the amputation risk was 26% higher for those less compliant with diabetes treatment. An increase of one point in the Wagner ulcer classification criteria corresponded to a 65% increase in the risk of amputation. Undergoing conservative, nonsurgical procedures prior to admission provided a 63% reduction in the risk of amputation. Knowledge of these factors is critical to enable multidisciplinary teams to develop treatment plans for these patients so as to prevent the need for amputation.http://dx.doi.org/10.1155/2016/8931508 |
| spellingShingle | Maria Teresa Verrone Quilici Fernando de Sá Del Fiol Alexandre Eduardo Franzin Vieira Maria Inês Toledo Risk Factors for Foot Amputation in Patients Hospitalized for Diabetic Foot Infection Journal of Diabetes Research |
| title | Risk Factors for Foot Amputation in Patients Hospitalized for Diabetic Foot Infection |
| title_full | Risk Factors for Foot Amputation in Patients Hospitalized for Diabetic Foot Infection |
| title_fullStr | Risk Factors for Foot Amputation in Patients Hospitalized for Diabetic Foot Infection |
| title_full_unstemmed | Risk Factors for Foot Amputation in Patients Hospitalized for Diabetic Foot Infection |
| title_short | Risk Factors for Foot Amputation in Patients Hospitalized for Diabetic Foot Infection |
| title_sort | risk factors for foot amputation in patients hospitalized for diabetic foot infection |
| url | http://dx.doi.org/10.1155/2016/8931508 |
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