A Zeolitic Imidazolate Framework-Based Antimicrobial Peptide Delivery System with Enhanced Anticancer Activity and Low Systemic Toxicity

A Zeolitic Imidazolate Framework-Based Antimicrobial Peptide Delivery System with Enhanced Anticancer Activity and Low Systemic Toxicity

Background: The clinical efficacies of anticancer drugs are limited by non-selective toxic effects on healthy tissues and low bioavailability in tumor tissue. Therefore, the development of vehicles that can selectively deliver and release drugs at the tumor site is critical for further improvements...

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Bibliographic Details
Main Authors: Jingwen Jiang, Kaderya Kaysar, Yanzhu Pan, Lijie Xia, Jinyao Li
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Pharmaceutics
Subjects:
ZIF-8
antibacterial peptide
drug delivery
pH response
anticancer
Online Access:https://www.mdpi.com/1999-4923/16/12/1591
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