Efficacy and safety of fluorescence navigation combined with 3D imaging in precise liver resection: A systematic review and meta-analysis
Objective: This study aimed to evaluate the effectiveness and safety of fluorescence navigation combined with three-dimensional imaging (FN&3DI) technology in precise liver resection. Methods: A systematic search was conducted in the PubMed, Web of Science, Embase, and Cochrane Library databases...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-02-01
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| Series: | Photodiagnosis and Photodynamic Therapy |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1572100024004824 |
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| author | Chunwei Xu Xinhua Cui Jiafei Che Xiaojing Shen Dingchao Chen |
| author_facet | Chunwei Xu Xinhua Cui Jiafei Che Xiaojing Shen Dingchao Chen |
| author_sort | Chunwei Xu |
| collection | DOAJ |
| description | Objective: This study aimed to evaluate the effectiveness and safety of fluorescence navigation combined with three-dimensional imaging (FN&3DI) technology in precise liver resection. Methods: A systematic search was conducted in the PubMed, Web of Science, Embase, and Cochrane Library databases for all English-language publications on fluorescence-guided navigation combined with three-dimensional (3D) imaging technology–assisted precise liver resection, with a cutoff date of July 2024. After assessing the quality of the included studies and extracting relevant data, a meta-analysis was performed using Stata 12.0 software. Results: A total of 6 studies involving 451 patients were included in this study, with 207 patients in the FN&3DI group and 244 patients in the conventional surgery (CS) group. The meta-analysis results showed that the FN&3DI group exhibited significantly lower values than the CS group in terms of intraoperative blood loss [mean difference (MD) = –97.90, 95 % confidence intervals (CI) = –151.15 to –44.66, P = 0.000], intraoperative blood transfusion rates [odds ratios (OR) = 2.96, 95 % CI = 1.71–5.10, P = 0.000], hospital stay (MD = –0.91, 95 % CI = –1.78 to –0.04, P = 0.041), and overall postoperative complications (OR = 1.68, 95 % CI = 1.11 to 2.53, P = 0.014). However, the FN&3DI group exhibited significantly longer surgery time (MD = 57.36, 95 % CI = 13.31–101.40, P = 0.011), but no statistically significant difference was noted in conversion rate, R0 resection margins, and postoperative recurrence between the two groups. Conclusion: Fluorescence navigation combined with 3D imaging technology is safe and feasible for guiding precise liver resection. |
| format | Article |
| id | doaj-art-e8e82e2715dd4c7ab8449f96117e6200 |
| institution | Kabale University |
| issn | 1572-1000 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Photodiagnosis and Photodynamic Therapy |
| spelling | doaj-art-e8e82e2715dd4c7ab8449f96117e62002025-02-01T04:11:44ZengElsevierPhotodiagnosis and Photodynamic Therapy1572-10002025-02-0151104446Efficacy and safety of fluorescence navigation combined with 3D imaging in precise liver resection: A systematic review and meta-analysisChunwei Xu0Xinhua Cui1Jiafei Che2Xiaojing Shen3Dingchao Chen4Department of General Surgery, Zhejiang Rongjun Hospital, Zhejiang JiaXing 314000, ChinaDepartment of General Surgery, Zhejiang Rongjun Hospital, Zhejiang JiaXing 314000, ChinaDepartment of General Surgery, Zhejiang Rongjun Hospital, Zhejiang JiaXing 314000, ChinaDepartment of General Surgery, Zhejiang Rongjun Hospital, Zhejiang JiaXing 314000, ChinaCorresponding author at: Department of General Surgery, Zhejiang Rongjun Hospital, Zhejiang Jiaxing 314000, China.; Department of General Surgery, Zhejiang Rongjun Hospital, Zhejiang JiaXing 314000, ChinaObjective: This study aimed to evaluate the effectiveness and safety of fluorescence navigation combined with three-dimensional imaging (FN&3DI) technology in precise liver resection. Methods: A systematic search was conducted in the PubMed, Web of Science, Embase, and Cochrane Library databases for all English-language publications on fluorescence-guided navigation combined with three-dimensional (3D) imaging technology–assisted precise liver resection, with a cutoff date of July 2024. After assessing the quality of the included studies and extracting relevant data, a meta-analysis was performed using Stata 12.0 software. Results: A total of 6 studies involving 451 patients were included in this study, with 207 patients in the FN&3DI group and 244 patients in the conventional surgery (CS) group. The meta-analysis results showed that the FN&3DI group exhibited significantly lower values than the CS group in terms of intraoperative blood loss [mean difference (MD) = –97.90, 95 % confidence intervals (CI) = –151.15 to –44.66, P = 0.000], intraoperative blood transfusion rates [odds ratios (OR) = 2.96, 95 % CI = 1.71–5.10, P = 0.000], hospital stay (MD = –0.91, 95 % CI = –1.78 to –0.04, P = 0.041), and overall postoperative complications (OR = 1.68, 95 % CI = 1.11 to 2.53, P = 0.014). However, the FN&3DI group exhibited significantly longer surgery time (MD = 57.36, 95 % CI = 13.31–101.40, P = 0.011), but no statistically significant difference was noted in conversion rate, R0 resection margins, and postoperative recurrence between the two groups. Conclusion: Fluorescence navigation combined with 3D imaging technology is safe and feasible for guiding precise liver resection.http://www.sciencedirect.com/science/article/pii/S1572100024004824Fluorescent navigationLiver resectionMeta-analysisThree-dimensional image |
| spellingShingle | Chunwei Xu Xinhua Cui Jiafei Che Xiaojing Shen Dingchao Chen Efficacy and safety of fluorescence navigation combined with 3D imaging in precise liver resection: A systematic review and meta-analysis Photodiagnosis and Photodynamic Therapy Fluorescent navigation Liver resection Meta-analysis Three-dimensional image |
| title | Efficacy and safety of fluorescence navigation combined with 3D imaging in precise liver resection: A systematic review and meta-analysis |
| title_full | Efficacy and safety of fluorescence navigation combined with 3D imaging in precise liver resection: A systematic review and meta-analysis |
| title_fullStr | Efficacy and safety of fluorescence navigation combined with 3D imaging in precise liver resection: A systematic review and meta-analysis |
| title_full_unstemmed | Efficacy and safety of fluorescence navigation combined with 3D imaging in precise liver resection: A systematic review and meta-analysis |
| title_short | Efficacy and safety of fluorescence navigation combined with 3D imaging in precise liver resection: A systematic review and meta-analysis |
| title_sort | efficacy and safety of fluorescence navigation combined with 3d imaging in precise liver resection a systematic review and meta analysis |
| topic | Fluorescent navigation Liver resection Meta-analysis Three-dimensional image |
| url | http://www.sciencedirect.com/science/article/pii/S1572100024004824 |
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