The corneal biomechanical changes of phacoemulsification in cataract patients: A systematic review and meta-analysis.
<h4>Purpose</h4>To evaluate the corneal biomechanical properties of phacoemulsification in the treatment of cataract patients.<h4>Methods</h4>Pertinent studies were searched in PubMed, EMBASE, Web of Science and clinicaltrials.gov., as of November 05, 2024. The reference list...
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Public Library of Science (PLoS)
2025-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0317179 |
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| author | Xinru Li Xiaofeng Li Lintong Tan Hu Chen Yuan Lai |
| author_facet | Xinru Li Xiaofeng Li Lintong Tan Hu Chen Yuan Lai |
| author_sort | Xinru Li |
| collection | DOAJ |
| description | <h4>Purpose</h4>To evaluate the corneal biomechanical properties of phacoemulsification in the treatment of cataract patients.<h4>Methods</h4>Pertinent studies were searched in PubMed, EMBASE, Web of Science and clinicaltrials.gov., as of November 05, 2024. The reference lists of related published reviews were included as well. This meta-analysis was performed with Stata Software and Review Manager, we used mean difference (MD) to evaluate the statistical consequence, using I2 statistic to assess the heterogeneity. Subgroup analysis were performed under the occurrences of high heterogeneity. We used eleven items to describe the characteristics of included studies, publication bias was performed with Egger's test. The quality assessment were evaluated with 3 items by Newcastle-Ottawa Scale (NOS) items.<h4>Results</h4>Thirteen eligible studies were identified for data synthesis and assessment. According to the result of meta-analysis, the central corneal thickness(CCT) (MD = 10.50, 95% CI: [5.01, 15.98]; P<0.05) and intraocular pressure(IOPg)(MD = -0.73, 95% CI: [-1.26, -0.19]; P<0.05) of cataract patients after phacoemulsification was significantly higher than the control groups. The values of corneal hysteresis(CH) (MD = -0.43, 95% CI: [-0.62, -0.23]; P<0.05) and corneal resistance factor(CRF) (MD = -0.49, 95% CI: [-0.64, -0.33]; P<0.05) after phacoemulsification surgery were statistically lower than the control groups. While the values of IOPcc did not show statistically different (MD = -0.13, 95% CI: [-0.67, 0.41]; P = 0.64).<h4>Conclusion</h4>Included data analysis indicated that the values of CCT, CH, CRF and IOPg showed statistical change in cataract patients after phacoemulsification surgeries compared with control groups. There is a correlation between corneal biomechanics and phacoemulsification surgeries. |
| format | Article |
| id | doaj-art-e8e77df224304166bd854db5c24eec85 |
| institution | Kabale University |
| issn | 1932-6203 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-e8e77df224304166bd854db5c24eec852025-02-05T05:32:07ZengPublic Library of Science (PLoS)PLoS ONE1932-62032025-01-01201e031717910.1371/journal.pone.0317179The corneal biomechanical changes of phacoemulsification in cataract patients: A systematic review and meta-analysis.Xinru LiXiaofeng LiLintong TanHu ChenYuan Lai<h4>Purpose</h4>To evaluate the corneal biomechanical properties of phacoemulsification in the treatment of cataract patients.<h4>Methods</h4>Pertinent studies were searched in PubMed, EMBASE, Web of Science and clinicaltrials.gov., as of November 05, 2024. The reference lists of related published reviews were included as well. This meta-analysis was performed with Stata Software and Review Manager, we used mean difference (MD) to evaluate the statistical consequence, using I2 statistic to assess the heterogeneity. Subgroup analysis were performed under the occurrences of high heterogeneity. We used eleven items to describe the characteristics of included studies, publication bias was performed with Egger's test. The quality assessment were evaluated with 3 items by Newcastle-Ottawa Scale (NOS) items.<h4>Results</h4>Thirteen eligible studies were identified for data synthesis and assessment. According to the result of meta-analysis, the central corneal thickness(CCT) (MD = 10.50, 95% CI: [5.01, 15.98]; P<0.05) and intraocular pressure(IOPg)(MD = -0.73, 95% CI: [-1.26, -0.19]; P<0.05) of cataract patients after phacoemulsification was significantly higher than the control groups. The values of corneal hysteresis(CH) (MD = -0.43, 95% CI: [-0.62, -0.23]; P<0.05) and corneal resistance factor(CRF) (MD = -0.49, 95% CI: [-0.64, -0.33]; P<0.05) after phacoemulsification surgery were statistically lower than the control groups. While the values of IOPcc did not show statistically different (MD = -0.13, 95% CI: [-0.67, 0.41]; P = 0.64).<h4>Conclusion</h4>Included data analysis indicated that the values of CCT, CH, CRF and IOPg showed statistical change in cataract patients after phacoemulsification surgeries compared with control groups. There is a correlation between corneal biomechanics and phacoemulsification surgeries.https://doi.org/10.1371/journal.pone.0317179 |
| spellingShingle | Xinru Li Xiaofeng Li Lintong Tan Hu Chen Yuan Lai The corneal biomechanical changes of phacoemulsification in cataract patients: A systematic review and meta-analysis. PLoS ONE |
| title | The corneal biomechanical changes of phacoemulsification in cataract patients: A systematic review and meta-analysis. |
| title_full | The corneal biomechanical changes of phacoemulsification in cataract patients: A systematic review and meta-analysis. |
| title_fullStr | The corneal biomechanical changes of phacoemulsification in cataract patients: A systematic review and meta-analysis. |
| title_full_unstemmed | The corneal biomechanical changes of phacoemulsification in cataract patients: A systematic review and meta-analysis. |
| title_short | The corneal biomechanical changes of phacoemulsification in cataract patients: A systematic review and meta-analysis. |
| title_sort | corneal biomechanical changes of phacoemulsification in cataract patients a systematic review and meta analysis |
| url | https://doi.org/10.1371/journal.pone.0317179 |
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