Bronchoalveolar lavage cell percentages as diagnostic markers of immune checkpoint inhibitor pneumonitis

Bronchoalveolar lavage cell percentages as diagnostic markers of immune checkpoint inhibitor pneumonitis

IntroductionDiagnostic biomarkers for immune checkpoint inhibitor pneumonitis (ICIP) are lacking. Bronchoalveolar lavage (BAL) lymphocytosis has been associated with ICIP, but studies have not evaluated BAL lymphocytosis as a diagnostic biomarker for ICIP.PurposeThis study aimed to measure the assoc...

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Main Authors: Mahnoor Mir, Felipe Soto, Pedro Antonio Amezcua Gomez, Rodrigo Del Rio Arroyo, Adarsh Suresh, Amber Su, Qiong Gan, John Stewart, Roberto Adachi, Diwakar D. Balachandran, Lara Bashoura, Roberto F. Casal, Burton F. Dickey, George A. Eapen, Scott E. Evans, Horiana Grosu, Carlos A. Jimenez, Julie Lin, David E. Ost, Bruce F. Sabath, Vickie R. Shannon, Aung Naing, Jianjun Gao, Jia Wu, Karthik Suresh, Saadia A. Faiz, Mehmet Altan, Ajay Sheshadri
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Medicine
Subjects:
immune check inhibitor (ICI)
BAL (bronchoalveolar lavage)
lymphocytosis
pneumonitis
eosinophilia
cell percentage
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1582714/full
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