Essential cell-intrinsic requirement for GMDS in T cell development

Essential cell-intrinsic requirement for GMDS in T cell development

Fucosylation, a type of glycosylation, is the attachment of a fucose to N-glycans, O-glycans and glycolipids, and is critical for the post-translational regulation of many essential pathways. Here we describe a mouse strain with an N-ethyl-N-nitrosourea-induced point mutation in the gene encoding gu...

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Bibliographic Details
Main Authors: Mehmet Yabas, Carla M. Roots, T. Daniel Andrews, Matt A. Field, Christopher C. Goodnow, Anselm Enders
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
fucosylation
glycosylation
GMDS
immune system
T cells
T cell development
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1598923/full
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