Prevalence of Osteoporosis and Its Associated Factors among Older Men with Type 2 Diabetes

This study investigated the prevalence of osteoporosis and its associated factors in old men with T2DM to identify risk factors for low BMD. We enrolled 93 old men (≥60 years of age) with T2DM and 125 healthy old men (controls) and collected data of their lifestyle, medical history, bone densitometr...

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Main Authors: Hai-ling Chen, Li-li Deng, Ju-fen Li
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2013/285729
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author Hai-ling Chen
Li-li Deng
Ju-fen Li
author_facet Hai-ling Chen
Li-li Deng
Ju-fen Li
author_sort Hai-ling Chen
collection DOAJ
description This study investigated the prevalence of osteoporosis and its associated factors in old men with T2DM to identify risk factors for low BMD. We enrolled 93 old men (≥60 years of age) with T2DM and 125 healthy old men (controls) and collected data of their lifestyle, medical history, bone densitometry, body weight, height, and blood pressure. Blood samples were collected for biochemical analyses. Urine samples were collected to determine 24 h urinary creatinine, albumin, and protein. Although no differences in age, blood pressure, waist-to-hip ratio, body mass index (BMI), and testosterone levels were observed, the prevalence of low BMD was significantly higher in the T2DM group compared to the control group. The risk of developing low BMD and fracture in T2DM subjects was increased by 46- and 26-fold, respectively, compared to control subjects. BMD of total spine and hip was positively correlated with BMI and negatively correlated with age, duration of diabetes, creatinine, and 24 h urinary albumin. So old men with T2DM have a greater risk of developing low BMD than old men without T2DM.
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spelling doaj-art-e8c3e3d1526b479ebb801c3429034b702025-02-03T01:28:58ZengWileyInternational Journal of Endocrinology1687-83371687-83452013-01-01201310.1155/2013/285729285729Prevalence of Osteoporosis and Its Associated Factors among Older Men with Type 2 DiabetesHai-ling Chen0Li-li Deng1Ju-fen Li2Department of Endocrinology, Jishuitan Hospital, Beijing 100035, ChinaDepartment of Endocrinology, Jishuitan Hospital, Beijing 100035, ChinaDepartment of Endocrinology, Jishuitan Hospital, Beijing 100035, ChinaThis study investigated the prevalence of osteoporosis and its associated factors in old men with T2DM to identify risk factors for low BMD. We enrolled 93 old men (≥60 years of age) with T2DM and 125 healthy old men (controls) and collected data of their lifestyle, medical history, bone densitometry, body weight, height, and blood pressure. Blood samples were collected for biochemical analyses. Urine samples were collected to determine 24 h urinary creatinine, albumin, and protein. Although no differences in age, blood pressure, waist-to-hip ratio, body mass index (BMI), and testosterone levels were observed, the prevalence of low BMD was significantly higher in the T2DM group compared to the control group. The risk of developing low BMD and fracture in T2DM subjects was increased by 46- and 26-fold, respectively, compared to control subjects. BMD of total spine and hip was positively correlated with BMI and negatively correlated with age, duration of diabetes, creatinine, and 24 h urinary albumin. So old men with T2DM have a greater risk of developing low BMD than old men without T2DM.http://dx.doi.org/10.1155/2013/285729
spellingShingle Hai-ling Chen
Li-li Deng
Ju-fen Li
Prevalence of Osteoporosis and Its Associated Factors among Older Men with Type 2 Diabetes
International Journal of Endocrinology
title Prevalence of Osteoporosis and Its Associated Factors among Older Men with Type 2 Diabetes
title_full Prevalence of Osteoporosis and Its Associated Factors among Older Men with Type 2 Diabetes
title_fullStr Prevalence of Osteoporosis and Its Associated Factors among Older Men with Type 2 Diabetes
title_full_unstemmed Prevalence of Osteoporosis and Its Associated Factors among Older Men with Type 2 Diabetes
title_short Prevalence of Osteoporosis and Its Associated Factors among Older Men with Type 2 Diabetes
title_sort prevalence of osteoporosis and its associated factors among older men with type 2 diabetes
url http://dx.doi.org/10.1155/2013/285729
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