Calanquinone A suppresses glioma progression via STAT3-mediated regulation of c-Myc and MMP9

Calanquinone A suppresses glioma progression via STAT3-mediated regulation of c-Myc and MMP9

Abstract Calanthe arisanensis, a traditional medicinal orchid, contains Calanquinone A, a quinone-type compound with reported anticancer properties. Glioblastoma multiforme (GBM) is a highly aggressive brain tumor with limited treatment options and a poor prognosis. This study investigates the molec...

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Bibliographic Details
Main Authors: Wen-Chi Hsieh, Chun-Yu Lin, Hsuan‐Cheng Wu, Huang-Wei Lo, Chiung-Yuan Ko, Jian-Ying Chuang, Tsung-I. Hsu, Tsui-Hwa Tseng, Teng-Wei Huang, Shao-Ming Wang
Format: Article
Language:English
Published: Springer 2025-08-01
Series:Discover Oncology
Subjects:
Calanthe arisanensis
Calanquinone a
Phytochemical
Glioblastoma multiforme
STAT3
Migration
Online Access:https://doi.org/10.1007/s12672-025-03279-4
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