Spectrophotometric Determination of Famciclovir and Racecodotril Using 2, 6-Dichloroquinone–Chlorimide
A simple, sensitive spectrophotometric method for the determination of Famciclovir and Racecodotril is developed. It is based on the formation of a colored oxidative coupling product between 2,6-dichloroquinone-chlorimide and the drug is described. The method has been extended to pharmaceutical prep...
Saved in:
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2007-01-01
|
Series: | E-Journal of Chemistry |
Online Access: | http://dx.doi.org/10.1155/2007/473705 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
_version_ | 1832560911538192384 |
---|---|
author | M. Vamsi Krishna P. V. Madhavi Latha D. Gowri Sankar |
author_facet | M. Vamsi Krishna P. V. Madhavi Latha D. Gowri Sankar |
author_sort | M. Vamsi Krishna |
collection | DOAJ |
description | A simple, sensitive spectrophotometric method for the determination of Famciclovir and Racecodotril is developed. It is based on the formation of a colored oxidative coupling product between 2,6-dichloroquinone-chlorimide and the drug is described. The method has been extended to pharmaceutical preparations. The absorption maxima and Beer’s law limits for Famciclovir are 500 nm, 20-100 µg/mL and for Racecodotril are 460 nm, 12.5-62.5 µg/mL. |
format | Article |
id | doaj-art-e8ae3da19a3e4765998c62959a128599 |
institution | Kabale University |
issn | 0973-4945 2090-9810 |
language | English |
publishDate | 2007-01-01 |
publisher | Wiley |
record_format | Article |
series | E-Journal of Chemistry |
spelling | doaj-art-e8ae3da19a3e4765998c62959a1285992025-02-03T01:26:32ZengWileyE-Journal of Chemistry0973-49452090-98102007-01-0141505210.1155/2007/473705Spectrophotometric Determination of Famciclovir and Racecodotril Using 2, 6-Dichloroquinone–ChlorimideM. Vamsi Krishna0P. V. Madhavi Latha1D. Gowri Sankar2Department of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530 003., IndiaDepartment of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530 003., IndiaDepartment of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530 003., IndiaA simple, sensitive spectrophotometric method for the determination of Famciclovir and Racecodotril is developed. It is based on the formation of a colored oxidative coupling product between 2,6-dichloroquinone-chlorimide and the drug is described. The method has been extended to pharmaceutical preparations. The absorption maxima and Beer’s law limits for Famciclovir are 500 nm, 20-100 µg/mL and for Racecodotril are 460 nm, 12.5-62.5 µg/mL.http://dx.doi.org/10.1155/2007/473705 |
spellingShingle | M. Vamsi Krishna P. V. Madhavi Latha D. Gowri Sankar Spectrophotometric Determination of Famciclovir and Racecodotril Using 2, 6-Dichloroquinone–Chlorimide E-Journal of Chemistry |
title | Spectrophotometric Determination of Famciclovir and Racecodotril Using 2, 6-Dichloroquinone–Chlorimide |
title_full | Spectrophotometric Determination of Famciclovir and Racecodotril Using 2, 6-Dichloroquinone–Chlorimide |
title_fullStr | Spectrophotometric Determination of Famciclovir and Racecodotril Using 2, 6-Dichloroquinone–Chlorimide |
title_full_unstemmed | Spectrophotometric Determination of Famciclovir and Racecodotril Using 2, 6-Dichloroquinone–Chlorimide |
title_short | Spectrophotometric Determination of Famciclovir and Racecodotril Using 2, 6-Dichloroquinone–Chlorimide |
title_sort | spectrophotometric determination of famciclovir and racecodotril using 2 6 dichloroquinone chlorimide |
url | http://dx.doi.org/10.1155/2007/473705 |
work_keys_str_mv | AT mvamsikrishna spectrophotometricdeterminationoffamciclovirandracecodotrilusing26dichloroquinonechlorimide AT pvmadhavilatha spectrophotometricdeterminationoffamciclovirandracecodotrilusing26dichloroquinonechlorimide AT dgowrisankar spectrophotometricdeterminationoffamciclovirandracecodotrilusing26dichloroquinonechlorimide |