COPB1-knockdown induced type I interferon signaling activation inhibits Chlamydia psittaci intracellular proliferation

COPB1-knockdown induced type I interferon signaling activation inhibits Chlamydia psittaci intracellular proliferation

ObjectiveChlamydia psittaci is a zoonotic pathogen that causes an acute disease known as psittacosis. To establish infection in host cells, Chlamydia manipulates the host cell’s membrane trafficking pathways.MethodsIn this study, using fluorescently labeled C. psittaci and screening a human membrane...

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Main Authors: Nana Li, Huiying Yang, Shan Zhang, Yufei Jiang, Yinhui Lin, Xiaoxiao Chen, Yuchen Zhang, Yonghui Yu, Xuan Ouyang, Yujun Cui, Yajun Song, Jun Jiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Microbiology
Subjects:
Chlamydia psittaci
COPB1
type I interferon
STING
Golgi
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1566239/full
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