In Vitro Preliminary Characterization of <i>Lactiplantibacillus plantarum</i> BG112 for Use as a Starter Culture for Industrial Dry-Fermented Meats

The objective of this study was to perform a preliminary in vitro characterization of <i>Lactiplantibacillus plantarum</i> BG112, assessing its safety and technological features for potential application as a culture starter for an industrial fermented dry meat product. In vitro assays a...

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Main Authors: María Inés Palacio, María Julia Ruiz, María Fernanda Vega, Analía Inés Etcheverría
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Fermentation
Subjects:
Online Access:https://www.mdpi.com/2311-5637/11/7/403
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author María Inés Palacio
María Julia Ruiz
María Fernanda Vega
Analía Inés Etcheverría
author_facet María Inés Palacio
María Julia Ruiz
María Fernanda Vega
Analía Inés Etcheverría
author_sort María Inés Palacio
collection DOAJ
description The objective of this study was to perform a preliminary in vitro characterization of <i>Lactiplantibacillus plantarum</i> BG112, assessing its safety and technological features for potential application as a culture starter for an industrial fermented dry meat product. In vitro assays assessed its viability, probiotic properties, and safety for use in food formulations. The strain was characterized through morphological and biochemical tests, carbohydrate fermentation profiling, and various in vitro assays based on FAO/WHO criteria for probiotic selection. These included proteolytic activity, auto-aggregation capacity, tolerance to simulated gastric juice and bile salts, antimicrobial activity, and resistance to sodium chloride, nitrite, and low pH. Safety evaluations were also performed by testing antibiotic susceptibility, hemolytic activity, and DNAse production. The results showed that <i>L. plantarum</i> BG112 exhibited strong tolerance to adverse environmental conditions typically found during sausage fermentation and ripening, along with significant inhibitory activity against pathogenic bacteria, such as <i>Escherichia coli</i> O157:H7, <i>Salmonella</i> Typhimurium, and <i>Staphylococcus aureus</i>. The strain also demonstrated no hemolytic or DNAse activity and presented a favorable antibiotic sensitivity profile, meeting key safety requirements for probiotic use. Further studies using meat matrices and in vivo models are needed to validate these findings. This study contributes to the early-stage selection of safe and technologically suitable strains for use in fermented meat products. These findings support the potential application of <i>L. plantarum</i> BG112 as a safe and effective starter culture in the development of high-value, premium fermented meat products, aligned with current consumer demand for health-enhancing and natural foods.
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spelling doaj-art-e8a27534c58d4f1f8d89d01fc4068fa42025-08-20T03:07:58ZengMDPI AGFermentation2311-56372025-07-0111740310.3390/fermentation11070403In Vitro Preliminary Characterization of <i>Lactiplantibacillus plantarum</i> BG112 for Use as a Starter Culture for Industrial Dry-Fermented MeatsMaría Inés Palacio0María Julia Ruiz1María Fernanda Vega2Analía Inés Etcheverría3Department of Technology and Food Quality, Veterinary Research Centre (CIVETAN), CONICET-CICPBA, Faculty of Veterinary Sciences, National University of the Center of the Province of Buenos Aires, Tandil CP7000, Buenos Aires, ArgentinaAnimal Health and Preventive Medicine, Veterinary Research Centre (CIVETAN), CONICET-CICPBA, Faculty of Veterinary Sciences, National University of the Center of the Province of Buenos Aires, Tandil CP7000, Buenos Aires, ArgentinaDepartment of Technology and Food Quality, Veterinary Research Centre (CIVETAN), CONICET-CICPBA, Faculty of Veterinary Sciences, National University of the Center of the Province of Buenos Aires, Tandil CP7000, Buenos Aires, ArgentinaAnimal Health and Preventive Medicine, Veterinary Research Centre (CIVETAN), CONICET-CICPBA, Faculty of Veterinary Sciences, National University of the Center of the Province of Buenos Aires, Tandil CP7000, Buenos Aires, ArgentinaThe objective of this study was to perform a preliminary in vitro characterization of <i>Lactiplantibacillus plantarum</i> BG112, assessing its safety and technological features for potential application as a culture starter for an industrial fermented dry meat product. In vitro assays assessed its viability, probiotic properties, and safety for use in food formulations. The strain was characterized through morphological and biochemical tests, carbohydrate fermentation profiling, and various in vitro assays based on FAO/WHO criteria for probiotic selection. These included proteolytic activity, auto-aggregation capacity, tolerance to simulated gastric juice and bile salts, antimicrobial activity, and resistance to sodium chloride, nitrite, and low pH. Safety evaluations were also performed by testing antibiotic susceptibility, hemolytic activity, and DNAse production. The results showed that <i>L. plantarum</i> BG112 exhibited strong tolerance to adverse environmental conditions typically found during sausage fermentation and ripening, along with significant inhibitory activity against pathogenic bacteria, such as <i>Escherichia coli</i> O157:H7, <i>Salmonella</i> Typhimurium, and <i>Staphylococcus aureus</i>. The strain also demonstrated no hemolytic or DNAse activity and presented a favorable antibiotic sensitivity profile, meeting key safety requirements for probiotic use. Further studies using meat matrices and in vivo models are needed to validate these findings. This study contributes to the early-stage selection of safe and technologically suitable strains for use in fermented meat products. These findings support the potential application of <i>L. plantarum</i> BG112 as a safe and effective starter culture in the development of high-value, premium fermented meat products, aligned with current consumer demand for health-enhancing and natural foods.https://www.mdpi.com/2311-5637/11/7/403dry-fermented sausagesprobiotic propertysafetyfermented foods
spellingShingle María Inés Palacio
María Julia Ruiz
María Fernanda Vega
Analía Inés Etcheverría
In Vitro Preliminary Characterization of <i>Lactiplantibacillus plantarum</i> BG112 for Use as a Starter Culture for Industrial Dry-Fermented Meats
Fermentation
dry-fermented sausages
probiotic property
safety
fermented foods
title In Vitro Preliminary Characterization of <i>Lactiplantibacillus plantarum</i> BG112 for Use as a Starter Culture for Industrial Dry-Fermented Meats
title_full In Vitro Preliminary Characterization of <i>Lactiplantibacillus plantarum</i> BG112 for Use as a Starter Culture for Industrial Dry-Fermented Meats
title_fullStr In Vitro Preliminary Characterization of <i>Lactiplantibacillus plantarum</i> BG112 for Use as a Starter Culture for Industrial Dry-Fermented Meats
title_full_unstemmed In Vitro Preliminary Characterization of <i>Lactiplantibacillus plantarum</i> BG112 for Use as a Starter Culture for Industrial Dry-Fermented Meats
title_short In Vitro Preliminary Characterization of <i>Lactiplantibacillus plantarum</i> BG112 for Use as a Starter Culture for Industrial Dry-Fermented Meats
title_sort in vitro preliminary characterization of i lactiplantibacillus plantarum i bg112 for use as a starter culture for industrial dry fermented meats
topic dry-fermented sausages
probiotic property
safety
fermented foods
url https://www.mdpi.com/2311-5637/11/7/403
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