STANDARDIZATION OF THE AMINO ACIDS TABLETS BY DIFFUSE REFLECTION IR SPECTROSCOPY
The possibility of using the infrared spectra of the diffuse reflection in the near and medium field of standardization and optimization of the technological process of tablet forms of aliphatic amino acids: butyric, β-alanine, γ-aminobutyric acid. Shown near infrared informative to normalize the mo...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
LLC Center of Pharmaceutical Analytics (LLC «CPHA»)
2019-01-01
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| Series: | Разработка и регистрация лекарственных средств |
| Subjects: | |
| Online Access: | https://www.pharmjournal.ru/jour/article/view/423 |
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| Summary: | The possibility of using the infrared spectra of the diffuse reflection in the near and medium field of standardization and optimization of the technological process of tablet forms of aliphatic amino acids: butyric, β-alanine, γ-aminobutyric acid. Shown near infrared informative to normalize the moisture content of a substance in the stages of the process, as well as in the finished dosage form. The paper analyzed the descriptiveness of the infrared spectra with respect to the tablet form of gamma-aminobutyric acid, glycine. The spectral data to differentiate the homologous amino acids: γ-aminobutyric, beta-aminopropanoic, and glycine. |
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| ISSN: | 2305-2066 2658-5049 |