Restricted mean survival time approach versus time-varying coefficient Cox model for quantifying treatment effect when hazards are non-proportional
Abstract Background Although the Cox time-varying coefficient (TVC) model has been developed to address non-proportional hazard (PH), its use remains underexplored. Instead, the restricted mean survival time (RMST) has been widely used in non-PH settings to quantify treatment effects using life expe...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-07-01
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| Series: | BMC Medical Research Methodology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12874-025-02608-z |
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