Combining ATAC-seq and RNA-seq reveals key genes for gonadal abnormalities in one-month-old XX-DSD pigs

Combining ATAC-seq and RNA-seq reveals key genes for gonadal abnormalities in one-month-old XX-DSD pigs

Abstract Background Disorders of Sex Development (DSD) are caused by congenital abnormalities in the chromosomes, and subsequent development of gonads or sexual anatomy. XX-DSD pigs exhibit a series of adverse symptoms such as sterility, genital infections, and decline in meat quality, leading to si...

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Bibliographic Details
Main Authors: Congying Yu, Bingzhou Zhong, Yuqiao Zhang, Haiquan Zhao, Jinhua Wu, Haiyi Yu, Hui Yu, Hua Li
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Genomics
Subjects:
Pig
RNA-seq
ATAC-seq
SOX9
XX-DSD
Online Access:https://doi.org/10.1186/s12864-025-11613-x
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