Reversible Cortical Blindness as a Prominent Manifestation of Cerebral Embolism due to Infective Endocarditis

Introduction. Infective endocarditis in the left heart may be complicated by stroke, due to embolisation from infectious valvular vegetations. Infarction of both occipital lobes, which are supplied by the posterior cerebral arteries, is infrequent, and is the cause of cortical blindness from lesion...

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Main Authors: Georgios P. Kranidiotis, Alexandra N. Gougoutsi, Theodoros A. Retsas, Maria I. Anastasiou-Nana
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2010/408471
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author Georgios P. Kranidiotis
Alexandra N. Gougoutsi
Theodoros A. Retsas
Maria I. Anastasiou-Nana
author_facet Georgios P. Kranidiotis
Alexandra N. Gougoutsi
Theodoros A. Retsas
Maria I. Anastasiou-Nana
author_sort Georgios P. Kranidiotis
collection DOAJ
description Introduction. Infective endocarditis in the left heart may be complicated by stroke, due to embolisation from infectious valvular vegetations. Infarction of both occipital lobes, which are supplied by the posterior cerebral arteries, is infrequent, and is the cause of cortical blindness from lesion of the visual cortex. Cortical blindness is characterized by intact pupillary reflexes, a normal fundoscopy, and, rarely, denial of visual loss. Case Presentation. We report the case of a 58-year-old woman, recipient of a mechanical aortic valve, who presented with fever, multiple organ dysfunction, and cortical blindness. Transesophageal echocardiography and blood cultures confirmed the diagnosis of infective endocarditis caused by methicillin-sensitive Staphylococcus aureus. Computed tomography of the brain without contrast revealed the presence of infarctions in both occipital lobes. It is noteworthy that the visual loss resolved after treatment of endocarditis. Conclusions. A stroke occurring in a patient presenting with fever and a history of valvular heart disease strongly suggests the presence of infective endocarditis. Bilateral thromboembolic infarcts of the occipital lobes cause cortical blindness, that can resolve after treatment of endocarditis.
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spelling doaj-art-e862a7ab307f4137a26be296b062850d2025-02-03T06:13:38ZengWileyCase Reports in Medicine1687-96271687-96352010-01-01201010.1155/2010/408471408471Reversible Cortical Blindness as a Prominent Manifestation of Cerebral Embolism due to Infective EndocarditisGeorgios P. Kranidiotis0Alexandra N. Gougoutsi1Theodoros A. Retsas2Maria I. Anastasiou-Nana3Department of Clinical Therapeutics, School of Medicine, University of Athens, “Alexandra” Hospital, 80 Vasilissis Sofias Av. 115 28 Athens, GreeceDepartment of Clinical Therapeutics, School of Medicine, University of Athens, “Alexandra” Hospital, 80 Vasilissis Sofias Av. 115 28 Athens, GreeceDepartment of Clinical Therapeutics, School of Medicine, University of Athens, “Alexandra” Hospital, 80 Vasilissis Sofias Av. 115 28 Athens, GreeceDepartment of Clinical Therapeutics, School of Medicine, University of Athens, “Alexandra” Hospital, 80 Vasilissis Sofias Av. 115 28 Athens, GreeceIntroduction. Infective endocarditis in the left heart may be complicated by stroke, due to embolisation from infectious valvular vegetations. Infarction of both occipital lobes, which are supplied by the posterior cerebral arteries, is infrequent, and is the cause of cortical blindness from lesion of the visual cortex. Cortical blindness is characterized by intact pupillary reflexes, a normal fundoscopy, and, rarely, denial of visual loss. Case Presentation. We report the case of a 58-year-old woman, recipient of a mechanical aortic valve, who presented with fever, multiple organ dysfunction, and cortical blindness. Transesophageal echocardiography and blood cultures confirmed the diagnosis of infective endocarditis caused by methicillin-sensitive Staphylococcus aureus. Computed tomography of the brain without contrast revealed the presence of infarctions in both occipital lobes. It is noteworthy that the visual loss resolved after treatment of endocarditis. Conclusions. A stroke occurring in a patient presenting with fever and a history of valvular heart disease strongly suggests the presence of infective endocarditis. Bilateral thromboembolic infarcts of the occipital lobes cause cortical blindness, that can resolve after treatment of endocarditis.http://dx.doi.org/10.1155/2010/408471
spellingShingle Georgios P. Kranidiotis
Alexandra N. Gougoutsi
Theodoros A. Retsas
Maria I. Anastasiou-Nana
Reversible Cortical Blindness as a Prominent Manifestation of Cerebral Embolism due to Infective Endocarditis
Case Reports in Medicine
title Reversible Cortical Blindness as a Prominent Manifestation of Cerebral Embolism due to Infective Endocarditis
title_full Reversible Cortical Blindness as a Prominent Manifestation of Cerebral Embolism due to Infective Endocarditis
title_fullStr Reversible Cortical Blindness as a Prominent Manifestation of Cerebral Embolism due to Infective Endocarditis
title_full_unstemmed Reversible Cortical Blindness as a Prominent Manifestation of Cerebral Embolism due to Infective Endocarditis
title_short Reversible Cortical Blindness as a Prominent Manifestation of Cerebral Embolism due to Infective Endocarditis
title_sort reversible cortical blindness as a prominent manifestation of cerebral embolism due to infective endocarditis
url http://dx.doi.org/10.1155/2010/408471
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