TNFα transport induced by dynamic loading alters biomechanics of intact intervertebral discs.

TNFα transport induced by dynamic loading alters biomechanics of intact intervertebral discs.

<h4>Objective</h4>Intervertebral disc (IVD) degeneration is an important contributor to the development of back pain, and a key factor relating pain and degeneration are the presence of pro-inflammatory cytokines and IVD motion. There is surprisingly limited understanding of how mechanic...

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Bibliographic Details
Main Authors: Benjamin A Walter, Morakot Likhitpanichkul, Svenja Illien-Junger, Peter J Roughley, Andrew C Hecht, James C Iatridis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0118358&type=printable
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