Metastatic Gastrointestinal Adenocarcinoma with Osteoblastic Activity: A Case Report of Esophageal and Colonic Primaries
Adenocarcinoma with osteoblastic metastases is classically seen in prostate, breast, and lung primaries. Less common primary sites include thyroid, kidney, and stomach. We present two cases of primary gastrointestinal adenocarcinoma with metastatic osteoblastic activity from two previously unreporte...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Pathology |
| Online Access: | http://dx.doi.org/10.1155/2016/1934759 |
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| _version_ | 1832558626376515584 |
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| author | Brett Matthew Lowenthal Ahmed S. Shabaik Mark A. Valasek |
| author_facet | Brett Matthew Lowenthal Ahmed S. Shabaik Mark A. Valasek |
| author_sort | Brett Matthew Lowenthal |
| collection | DOAJ |
| description | Adenocarcinoma with osteoblastic metastases is classically seen in prostate, breast, and lung primaries. Less common primary sites include thyroid, kidney, and stomach. We present two cases of primary gastrointestinal adenocarcinoma with metastatic osteoblastic activity from two previously unreported sites. The first case represents an esophageal adenocarcinoma arising in a background of intestinal metaplasia that metastasized with osteoblastic activity to the deltoid muscle. The second case demonstrates a Stage IV sigmoid colon adenocarcinoma with osteoblastic metastases to the liver and lymph nodes. The findings indicate that metastases from various gastrointestinal primary adenocarcinomas can have prominent bone formation. |
| format | Article |
| id | doaj-art-e83d1f3a16d945e9a9aaadf0c2fa9f9d |
| institution | Kabale University |
| issn | 2090-6781 2090-679X |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pathology |
| spelling | doaj-art-e83d1f3a16d945e9a9aaadf0c2fa9f9d2025-02-03T01:32:04ZengWileyCase Reports in Pathology2090-67812090-679X2016-01-01201610.1155/2016/19347591934759Metastatic Gastrointestinal Adenocarcinoma with Osteoblastic Activity: A Case Report of Esophageal and Colonic PrimariesBrett Matthew Lowenthal0Ahmed S. Shabaik1Mark A. Valasek2Department of Pathology, University of California, San Diego, 200 West Arbor Drive, MC 8320, San Diego, CA 92103, USADepartment of Pathology, University of California, San Diego, 200 West Arbor Drive, MC 8320, San Diego, CA 92103, USADepartment of Pathology, University of California, San Diego, 200 West Arbor Drive, MC 8320, San Diego, CA 92103, USAAdenocarcinoma with osteoblastic metastases is classically seen in prostate, breast, and lung primaries. Less common primary sites include thyroid, kidney, and stomach. We present two cases of primary gastrointestinal adenocarcinoma with metastatic osteoblastic activity from two previously unreported sites. The first case represents an esophageal adenocarcinoma arising in a background of intestinal metaplasia that metastasized with osteoblastic activity to the deltoid muscle. The second case demonstrates a Stage IV sigmoid colon adenocarcinoma with osteoblastic metastases to the liver and lymph nodes. The findings indicate that metastases from various gastrointestinal primary adenocarcinomas can have prominent bone formation.http://dx.doi.org/10.1155/2016/1934759 |
| spellingShingle | Brett Matthew Lowenthal Ahmed S. Shabaik Mark A. Valasek Metastatic Gastrointestinal Adenocarcinoma with Osteoblastic Activity: A Case Report of Esophageal and Colonic Primaries Case Reports in Pathology |
| title | Metastatic Gastrointestinal Adenocarcinoma with Osteoblastic Activity: A Case Report of Esophageal and Colonic Primaries |
| title_full | Metastatic Gastrointestinal Adenocarcinoma with Osteoblastic Activity: A Case Report of Esophageal and Colonic Primaries |
| title_fullStr | Metastatic Gastrointestinal Adenocarcinoma with Osteoblastic Activity: A Case Report of Esophageal and Colonic Primaries |
| title_full_unstemmed | Metastatic Gastrointestinal Adenocarcinoma with Osteoblastic Activity: A Case Report of Esophageal and Colonic Primaries |
| title_short | Metastatic Gastrointestinal Adenocarcinoma with Osteoblastic Activity: A Case Report of Esophageal and Colonic Primaries |
| title_sort | metastatic gastrointestinal adenocarcinoma with osteoblastic activity a case report of esophageal and colonic primaries |
| url | http://dx.doi.org/10.1155/2016/1934759 |
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