Multi-ancestry genome-wide association analyses: a comparison of meta- and mega-analyses in the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study
Abstract Background There is increasing need for effective incorporation of high-dimensional genetics data from individuals with varied ancestry in genome-wide association (GWAS) analyses. Classically, multi-ancestry GWAS analyses are performed using statistical meta-analysis to combine results cond...
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Main Authors: | Alan Kuang, Marie-France Hivert, M. Geoffrey Hayes, William L. Lowe, Denise M. Scholtens |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-01-01
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Series: | BMC Genomics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12864-025-11229-1 |
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