Functional Properties and Molecular Architecture of Leukotriene A4 Hydrolase, a Pivotal Catalyst of Chemotactic Leukotriene Formation
The leukotrienes are a family of lipid mediators involved in inflammation and allergy. Leukotriene B4 is a classical chemoattractant, which triggers adherence and aggregation of leukocytes to the endothelium at only nM concentrations. In addition, leukotriene B4 modulates immune responses, participa...
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Main Authors: | Jesper Z. Haeggström, Pär Nordlund, Marjolein M.G.M. Thunnissen |
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Format: | Article |
Language: | English |
Published: |
Wiley
2002-01-01
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Series: | The Scientific World Journal |
Online Access: | http://dx.doi.org/10.1100/tsw.2002.810 |
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