Pancreatic Myeloid Sarcoma Causing Obstructive Jaundice: A Case Report and Literature Review
Myeloid sarcoma (MS) is an extramedullary manifestation of acute myeloid leukemia (AML) and commonly occurs in sites such as the lymph nodes, skin, soft tissues, and bone. It more rarely manifests in the pancreas, with less than 20 cases reported in the literature since 1987. Despite its rarity, MS...
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| Format: | Article |
| Language: | English |
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Wiley
2024-01-01
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| Series: | Case Reports in Gastrointestinal Medicine |
| Online Access: | http://dx.doi.org/10.1155/2024/5513857 |
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| author | Laura E. Lavette Angela G. Niehaus Clancy J. Clark Jason D. Conway Girish Mishra Darius A. Jahann |
| author_facet | Laura E. Lavette Angela G. Niehaus Clancy J. Clark Jason D. Conway Girish Mishra Darius A. Jahann |
| author_sort | Laura E. Lavette |
| collection | DOAJ |
| description | Myeloid sarcoma (MS) is an extramedullary manifestation of acute myeloid leukemia (AML) and commonly occurs in sites such as the lymph nodes, skin, soft tissues, and bone. It more rarely manifests in the pancreas, with less than 20 cases reported in the literature since 1987. Despite its rarity, MS should be considered in the differential diagnosis of a soft tissue mass causing obstructive jaundice, especially if the patient has a known hematologic disease. Isolated cases of pancreatic MS have been known to progress to AML; therefore, it is crucial to differentiate MS from more common diagnoses, such as pancreatic cancer or pancreatitis. This is a case of a 70-year-old male with symptomatic obstructive jaundice secondary to pancreatic MS, ultimately requiring endoscopic ultrasound (EUS) and endoscopic retrograde cholangiopancreatography (ERCP) for diagnosis and management. Also included is a comprehensive review of previous case reports with similar clinical presentations, management, and treatment of pancreatic MS. |
| format | Article |
| id | doaj-art-e814835c858342d39b70c536c5b62bfd |
| institution | Kabale University |
| issn | 2090-6536 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Gastrointestinal Medicine |
| spelling | doaj-art-e814835c858342d39b70c536c5b62bfd2025-02-03T05:55:28ZengWileyCase Reports in Gastrointestinal Medicine2090-65362024-01-01202410.1155/2024/5513857Pancreatic Myeloid Sarcoma Causing Obstructive Jaundice: A Case Report and Literature ReviewLaura E. Lavette0Angela G. Niehaus1Clancy J. Clark2Jason D. Conway3Girish Mishra4Darius A. Jahann5Department of Internal MedicineDepartment of PathologyDepartment of SurgeryDepartment of MedicineDepartment of MedicineDepartment of MedicineMyeloid sarcoma (MS) is an extramedullary manifestation of acute myeloid leukemia (AML) and commonly occurs in sites such as the lymph nodes, skin, soft tissues, and bone. It more rarely manifests in the pancreas, with less than 20 cases reported in the literature since 1987. Despite its rarity, MS should be considered in the differential diagnosis of a soft tissue mass causing obstructive jaundice, especially if the patient has a known hematologic disease. Isolated cases of pancreatic MS have been known to progress to AML; therefore, it is crucial to differentiate MS from more common diagnoses, such as pancreatic cancer or pancreatitis. This is a case of a 70-year-old male with symptomatic obstructive jaundice secondary to pancreatic MS, ultimately requiring endoscopic ultrasound (EUS) and endoscopic retrograde cholangiopancreatography (ERCP) for diagnosis and management. Also included is a comprehensive review of previous case reports with similar clinical presentations, management, and treatment of pancreatic MS.http://dx.doi.org/10.1155/2024/5513857 |
| spellingShingle | Laura E. Lavette Angela G. Niehaus Clancy J. Clark Jason D. Conway Girish Mishra Darius A. Jahann Pancreatic Myeloid Sarcoma Causing Obstructive Jaundice: A Case Report and Literature Review Case Reports in Gastrointestinal Medicine |
| title | Pancreatic Myeloid Sarcoma Causing Obstructive Jaundice: A Case Report and Literature Review |
| title_full | Pancreatic Myeloid Sarcoma Causing Obstructive Jaundice: A Case Report and Literature Review |
| title_fullStr | Pancreatic Myeloid Sarcoma Causing Obstructive Jaundice: A Case Report and Literature Review |
| title_full_unstemmed | Pancreatic Myeloid Sarcoma Causing Obstructive Jaundice: A Case Report and Literature Review |
| title_short | Pancreatic Myeloid Sarcoma Causing Obstructive Jaundice: A Case Report and Literature Review |
| title_sort | pancreatic myeloid sarcoma causing obstructive jaundice a case report and literature review |
| url | http://dx.doi.org/10.1155/2024/5513857 |
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