Antimicrobial activity, synthesis, and docking study of some novel arylazo-1,3-thiazolopyrimidine and arylazo-1,3-thiazolopyridopyrimidine derivatives

Antimicrobial activity, synthesis, and docking study of some novel arylazo-1,3-thiazolopyrimidine and arylazo-1,3-thiazolopyridopyrimidine derivatives

Abstract In this study, a new series of aryl azo thiazolopyrimidine and thiazolopyridopyrimidine derivatives was synthesized using novel 6-aryl-4-(2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-9-yl)-3,4-dihydropyrimidine-2(1H)-thione and 5-aryl-7-(2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinoli...

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Main Authors: Jihan Qurban, Sara A. Alqarni, Adel I. Alalawy, Nawaa Ali H. Alshammari, Gadeer R. S. Ashour, Maryam M. Alnoman, Hanadi A. Katuah, Nashwa M. El-Metwaly
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Chemistry
Subjects:
Chalcones
Pyrimidinethion derivatives
Antibacterial activity
Molecular docking
Online Access:https://doi.org/10.1186/s13065-025-01506-1
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