Bone density may affect primary stability of anterior cruciate ligament reconstruction when organic core bone plug fixation technique used

Abstract Purpose Core Bone Plug Fixation (CBPF) technique is an implant‐less methodology for ACL reconstruction. This study investigates the effect of bone density on CBPF stability to identify the bone quality that is likely to benefit from this technique. Methods Artificial blocks with 160 (Group...

Full description

Saved in:
Bibliographic Details
Main Authors: Pouya Dehestani, Farzam Farahmand, Amirhossein Borjali, Kaveh Bashti, Mahmoud Chizari
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Journal of Experimental Orthopaedics
Subjects:
Online Access:https://doi.org/10.1186/s40634-021-00441-z
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850156702294343680
author Pouya Dehestani
Farzam Farahmand
Amirhossein Borjali
Kaveh Bashti
Mahmoud Chizari
author_facet Pouya Dehestani
Farzam Farahmand
Amirhossein Borjali
Kaveh Bashti
Mahmoud Chizari
author_sort Pouya Dehestani
collection DOAJ
description Abstract Purpose Core Bone Plug Fixation (CBPF) technique is an implant‐less methodology for ACL reconstruction. This study investigates the effect of bone density on CBPF stability to identify the bone quality that is likely to benefit from this technique. Methods Artificial blocks with 160 (Group 1), 240 (Group 2), and 320 (Group 3) kg/m3 densities were used to simulate human bone with diverse qualities. These groups are representative of the elderly, middle age and young people, respectively. A tunnel was made in each test sample using a cannulated drill bit which enabled harvesting the core bone plug intact. Fresh animal tendon grafts were prepared and passed through the tunnel, so the core bone was pushed in to secure the tendon. The fixation stability was tested by applying a cyclic load following by a pullout load until the failure occurred. The selected group was compared with interference screw fixation technique as a gold standard method in ACL reconstruction. Results The Group 2 stiffness and yield strength were significantly larger than Group 1. The graft slippage of Group 1 was significantly less than Group 3. The ultimate strengths were 310 N and 363 N, in Groups 2 and 3, significantly larger than that of Group 1. The ultimate strength in fixation by interference screw was 693.18 N, significantly larger than the bone plug method. Conclusions The stability of CBPF was greatly affected by bone density. This technique is more suitable for young and middle‐aged people. With further improvements, the CBPF might be an alternative ACL reconstruction technique for patients with good bone quality. Clinical relevance The CBPF technique offers an implant‐less organic ACL reconstruction technique with numerous advantages and likely would speed up the healing process by using the patient’s own bones and tissues rather than any non‐biologic fixations.
format Article
id doaj-art-e7ff53d8265a492f97b7e5bcd1ea177e
institution OA Journals
issn 2197-1153
language English
publishDate 2022-01-01
publisher Wiley
record_format Article
series Journal of Experimental Orthopaedics
spelling doaj-art-e7ff53d8265a492f97b7e5bcd1ea177e2025-08-20T02:24:25ZengWileyJournal of Experimental Orthopaedics2197-11532022-01-0191n/an/a10.1186/s40634-021-00441-zBone density may affect primary stability of anterior cruciate ligament reconstruction when organic core bone plug fixation technique usedPouya Dehestani0Farzam Farahmand1Amirhossein Borjali2Kaveh Bashti3Mahmoud Chizari4Department of Mechanical EngineeringSharif University of TechnologyTehranIranDepartment of Mechanical EngineeringSharif University of TechnologyTehranIranDepartment of Mechanical EngineeringSharif University of TechnologyTehranIranDepartment of OrthopedicsDivision of Knee SurgeryShariati HospitalTehran University of Medical SciencesTehranIranDepartment of Mechanical EngineeringSharif University of TechnologyTehranIranAbstract Purpose Core Bone Plug Fixation (CBPF) technique is an implant‐less methodology for ACL reconstruction. This study investigates the effect of bone density on CBPF stability to identify the bone quality that is likely to benefit from this technique. Methods Artificial blocks with 160 (Group 1), 240 (Group 2), and 320 (Group 3) kg/m3 densities were used to simulate human bone with diverse qualities. These groups are representative of the elderly, middle age and young people, respectively. A tunnel was made in each test sample using a cannulated drill bit which enabled harvesting the core bone plug intact. Fresh animal tendon grafts were prepared and passed through the tunnel, so the core bone was pushed in to secure the tendon. The fixation stability was tested by applying a cyclic load following by a pullout load until the failure occurred. The selected group was compared with interference screw fixation technique as a gold standard method in ACL reconstruction. Results The Group 2 stiffness and yield strength were significantly larger than Group 1. The graft slippage of Group 1 was significantly less than Group 3. The ultimate strengths were 310 N and 363 N, in Groups 2 and 3, significantly larger than that of Group 1. The ultimate strength in fixation by interference screw was 693.18 N, significantly larger than the bone plug method. Conclusions The stability of CBPF was greatly affected by bone density. This technique is more suitable for young and middle‐aged people. With further improvements, the CBPF might be an alternative ACL reconstruction technique for patients with good bone quality. Clinical relevance The CBPF technique offers an implant‐less organic ACL reconstruction technique with numerous advantages and likely would speed up the healing process by using the patient’s own bones and tissues rather than any non‐biologic fixations.https://doi.org/10.1186/s40634-021-00441-zCore bone plug fixationACL reconstructionBone densityImplant‐lessTensile test
spellingShingle Pouya Dehestani
Farzam Farahmand
Amirhossein Borjali
Kaveh Bashti
Mahmoud Chizari
Bone density may affect primary stability of anterior cruciate ligament reconstruction when organic core bone plug fixation technique used
Journal of Experimental Orthopaedics
Core bone plug fixation
ACL reconstruction
Bone density
Implant‐less
Tensile test
title Bone density may affect primary stability of anterior cruciate ligament reconstruction when organic core bone plug fixation technique used
title_full Bone density may affect primary stability of anterior cruciate ligament reconstruction when organic core bone plug fixation technique used
title_fullStr Bone density may affect primary stability of anterior cruciate ligament reconstruction when organic core bone plug fixation technique used
title_full_unstemmed Bone density may affect primary stability of anterior cruciate ligament reconstruction when organic core bone plug fixation technique used
title_short Bone density may affect primary stability of anterior cruciate ligament reconstruction when organic core bone plug fixation technique used
title_sort bone density may affect primary stability of anterior cruciate ligament reconstruction when organic core bone plug fixation technique used
topic Core bone plug fixation
ACL reconstruction
Bone density
Implant‐less
Tensile test
url https://doi.org/10.1186/s40634-021-00441-z
work_keys_str_mv AT pouyadehestani bonedensitymayaffectprimarystabilityofanteriorcruciateligamentreconstructionwhenorganiccoreboneplugfixationtechniqueused
AT farzamfarahmand bonedensitymayaffectprimarystabilityofanteriorcruciateligamentreconstructionwhenorganiccoreboneplugfixationtechniqueused
AT amirhosseinborjali bonedensitymayaffectprimarystabilityofanteriorcruciateligamentreconstructionwhenorganiccoreboneplugfixationtechniqueused
AT kavehbashti bonedensitymayaffectprimarystabilityofanteriorcruciateligamentreconstructionwhenorganiccoreboneplugfixationtechniqueused
AT mahmoudchizari bonedensitymayaffectprimarystabilityofanteriorcruciateligamentreconstructionwhenorganiccoreboneplugfixationtechniqueused