Organs Blood Flow during Elevation of Body Temperature in Sevoflurane Anesthetized Rats

The aim of this study is to investigate how elevation of body temperature changes organs blood flow during sevoflurane anesthesia. We conducted in vivo research on 14 male Wistar rats to monitor pulse rate and arterial blood pressure and measure hepatic, small intestinal, renal, and descending aorti...

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Main Authors: Koichi Shimo, Ko Takakura, Kenji Shigemi
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Anesthesiology Research and Practice
Online Access:http://dx.doi.org/10.1155/2017/6182350
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author Koichi Shimo
Ko Takakura
Kenji Shigemi
author_facet Koichi Shimo
Ko Takakura
Kenji Shigemi
author_sort Koichi Shimo
collection DOAJ
description The aim of this study is to investigate how elevation of body temperature changes organs blood flow during sevoflurane anesthesia. We conducted in vivo research on 14 male Wistar rats to monitor pulse rate and arterial blood pressure and measure hepatic, small intestinal, renal, and descending aortic blood flow using a laser Doppler blood flowmeter. We assessed the changes in organ blood flow, pulse rate, and arterial blood pressure during elevation of the rats’ body temperatures up to 41.5°C under anesthesia with 2.0% or 3.0% sevoflurane. We concluded that elevation of body temperature up to 39.5°C does not change hepatic, small intestinal, and renal blood flow during 2.0 and 3.0% sevoflurane anesthesia.
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institution Kabale University
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publishDate 2017-01-01
publisher Wiley
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series Anesthesiology Research and Practice
spelling doaj-art-e7f215871bc8411c97f43a020746de732025-02-03T05:45:00ZengWileyAnesthesiology Research and Practice1687-69621687-69702017-01-01201710.1155/2017/61823506182350Organs Blood Flow during Elevation of Body Temperature in Sevoflurane Anesthetized RatsKoichi Shimo0Ko Takakura1Kenji Shigemi2Department of Anesthesiology and Reanimatology, Faculty of Medical Sciences, Fukui University, Fukui, JapanDepartment of Anesthesiology, Gifu Prefectural Gero Hot Spring Hospital, Gifu, JapanDepartment of Anesthesiology and Reanimatology, Faculty of Medical Sciences, Fukui University, Fukui, JapanThe aim of this study is to investigate how elevation of body temperature changes organs blood flow during sevoflurane anesthesia. We conducted in vivo research on 14 male Wistar rats to monitor pulse rate and arterial blood pressure and measure hepatic, small intestinal, renal, and descending aortic blood flow using a laser Doppler blood flowmeter. We assessed the changes in organ blood flow, pulse rate, and arterial blood pressure during elevation of the rats’ body temperatures up to 41.5°C under anesthesia with 2.0% or 3.0% sevoflurane. We concluded that elevation of body temperature up to 39.5°C does not change hepatic, small intestinal, and renal blood flow during 2.0 and 3.0% sevoflurane anesthesia.http://dx.doi.org/10.1155/2017/6182350
spellingShingle Koichi Shimo
Ko Takakura
Kenji Shigemi
Organs Blood Flow during Elevation of Body Temperature in Sevoflurane Anesthetized Rats
Anesthesiology Research and Practice
title Organs Blood Flow during Elevation of Body Temperature in Sevoflurane Anesthetized Rats
title_full Organs Blood Flow during Elevation of Body Temperature in Sevoflurane Anesthetized Rats
title_fullStr Organs Blood Flow during Elevation of Body Temperature in Sevoflurane Anesthetized Rats
title_full_unstemmed Organs Blood Flow during Elevation of Body Temperature in Sevoflurane Anesthetized Rats
title_short Organs Blood Flow during Elevation of Body Temperature in Sevoflurane Anesthetized Rats
title_sort organs blood flow during elevation of body temperature in sevoflurane anesthetized rats
url http://dx.doi.org/10.1155/2017/6182350
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AT kotakakura organsbloodflowduringelevationofbodytemperatureinsevofluraneanesthetizedrats
AT kenjishigemi organsbloodflowduringelevationofbodytemperatureinsevofluraneanesthetizedrats