Population substructure and control selection in genome-wide association studies.
Determination of the relevance of both demanding classical epidemiologic criteria for control selection and robust handling of population stratification (PS) represents a major challenge in the design and analysis of genome-wide association studies (GWAS). Empirical data from two GWAS in European Am...
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| Main Authors: | Kai Yu, Zhaoming Wang, Qizhai Li, Sholom Wacholder, David J Hunter, Robert N Hoover, Stephen Chanock, Gilles Thomas |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2008-07-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0002551&type=printable |
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