Targeting β2-adrenergic receptor reduces UV-induced cutaneous damage and inflammation in a murine model

Targeting β2-adrenergic receptor reduces UV-induced cutaneous damage and inflammation in a murine model

Preclinical studies demonstrated that the β-adrenergic receptor antagonists (β-blockers) inhibit skin damage and cancer development induced by ultraviolet (UV) radiation, but the mechanism remains unknown. β2-adrenergic receptor (β2-AR) is the predominant adrenergic receptor expressed on skin kerati...

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Bibliographic Details
Main Authors: Ayaz Shahid, Rita Miwalian, Bradley T. Andresen, Steven Cole, Ying Huang
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Journal of Photochemistry and Photobiology
Subjects:
β2-AR
Inflammation
Skin
SKH-1
UV radiation
Online Access:http://www.sciencedirect.com/science/article/pii/S2666469025000077
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