Regulation of EMT-MET and chemoresistance by the Lc3Cer-synthase B3GNT5

Abstract Background Glycosphingolipids (GSL) are essential components of the plasma membrane where they are known to play key structural and functional roles and are known to influence molecular processes involved in cancer malignancy, including multi-drug chemoresistance, the epithelial to mesenchy...

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Bibliographic Details
Main Authors: Laura E. Clark, Katherine Hylton Rorie, Amanda J. G. Dickinson, Santiago Lima
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Cancer
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Online Access:https://doi.org/10.1186/s12885-025-14717-5
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