Simmering Innards: Does Irritable Bowl Syndrome Have an Immunological Basis?

Not so long ago, physicians construed the irritable bowel syndrome (IBS) as being a neurotic trait: it was all in the head. Today most clinicians believe that the main abnormality lies in the brain (and spinal cord), which reacts abnormally to stimuli from the gut. Recent studies are identifying...

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Main Authors: Christopher N Andrews, Eldon A Shaffer
Format: Article
Language:English
Published: Wiley 2004-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2004/707528
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author Christopher N Andrews
Eldon A Shaffer
author_facet Christopher N Andrews
Eldon A Shaffer
author_sort Christopher N Andrews
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description Not so long ago, physicians construed the irritable bowel syndrome (IBS) as being a neurotic trait: it was all in the head. Today most clinicians believe that the main abnormality lies in the brain (and spinal cord), which reacts abnormally to stimuli from the gut. Recent studies are identifying a basis for these neural changes - low grade inflammation in the gut - which may play a key role in IBS.
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spelling doaj-art-e7ccfc766ee74e3496b1731ff6331ca42025-02-03T01:00:49ZengWileyCanadian Journal of Gastroenterology0835-79002004-01-01181060160310.1155/2004/707528Simmering Innards: Does Irritable Bowl Syndrome Have an Immunological Basis?Christopher N Andrews0Eldon A Shaffer1Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota, USADivision of Gastroenterology, University of Calgary, Calgary, Alberta, CanadaNot so long ago, physicians construed the irritable bowel syndrome (IBS) as being a neurotic trait: it was all in the head. Today most clinicians believe that the main abnormality lies in the brain (and spinal cord), which reacts abnormally to stimuli from the gut. Recent studies are identifying a basis for these neural changes - low grade inflammation in the gut - which may play a key role in IBS.http://dx.doi.org/10.1155/2004/707528
spellingShingle Christopher N Andrews
Eldon A Shaffer
Simmering Innards: Does Irritable Bowl Syndrome Have an Immunological Basis?
Canadian Journal of Gastroenterology
title Simmering Innards: Does Irritable Bowl Syndrome Have an Immunological Basis?
title_full Simmering Innards: Does Irritable Bowl Syndrome Have an Immunological Basis?
title_fullStr Simmering Innards: Does Irritable Bowl Syndrome Have an Immunological Basis?
title_full_unstemmed Simmering Innards: Does Irritable Bowl Syndrome Have an Immunological Basis?
title_short Simmering Innards: Does Irritable Bowl Syndrome Have an Immunological Basis?
title_sort simmering innards does irritable bowl syndrome have an immunological basis
url http://dx.doi.org/10.1155/2004/707528
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