Transcriptomic, mutational and structural bioinformatics approaches to explore the therapeutic role of FAP in predominant cancer types

Abstract Fibroblast activating protein (FAP) is a cell surface marker of cancer-associated fibroblasts with a distinct pro-tumorigenic role. The present study analyzed the pan-cancer expression; and clinical and mutational profiles of the FAP coding gene. Molecular dynamics simulation (MDS) decipher...

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Bibliographic Details
Main Authors: Gayathri Ashok, Abdullah F. AlAsmari, Fawaz AlAsmari, Paul Livingstone, Anand Anbarasu, Sudha Ramaiah
Format: Article
Language:English
Published: Springer 2024-11-01
Series:Discover Oncology
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Online Access:https://doi.org/10.1007/s12672-024-01531-x
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