Endosomal H<sub>2</sub>O<sub>2</sub> Molecules Act as Signaling Mediators in Akt/PKB Activation

Endosomal H<sub>2</sub>O<sub>2</sub> Molecules Act as Signaling Mediators in Akt/PKB Activation

Receptor-mediated endocytosis (RME) is a commonly recognized receptor internalization process of receptor degradation or recycling. However, recent studies have supported that RME is closely related to signal propagation and amplification from the plasma membrane to the cytosol. Few studies have elu...

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Bibliographic Details
Main Authors: Sujin Park, Chaewon Kim, Sukyeong Heo, Dongmin Kang
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Antioxidants
Subjects:
receptor-mediated endocytosis
hydrogen peroxide
Akt/PKB
early endosome
the Leucine zipper motif 1 (APPL1)
Online Access:https://www.mdpi.com/2076-3921/14/5/594
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