Transcriptomic profiling of cumulus cells reveals dysregulated genes and pathways in PCOS-related infertility
Abstract Background Polycystic ovarian syndrome (PCOS) is a leading cause of infertility and metabolic dysfunction in women, characterized by hyperandrogenism, anovulation, and insulin resistance. Cumulus cells play a crucial role in folliculogenesis and oocyte maturation, necessitating a deeper und...
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| Main Authors: | Akeem Babatunde Sikiru, Nurulfiza Mat Isa, Kasim Sakran Abass, Muibat Adesola Adeniran, Stephen Sunday Acheneje Egena, Karimot Akinola |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SpringerOpen
2025-08-01
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| Series: | Middle East Fertility Society Journal |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s43043-025-00241-w |
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