ADELLE: A global testing method for trans-eQTL mapping.
Understanding the genetic regulatory mechanisms of gene expression is an ongoing challenge. Genetic variants that are associated with expression levels are readily identified when they are proximal to the gene (i.e., cis-eQTLs), but SNPs distant from the gene whose expression levels they are associa...
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Main Authors: | Takintayo Akinbiyi, Mary Sara McPeek, Mark Abney |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2025-01-01
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Series: | PLoS Genetics |
Online Access: | https://doi.org/10.1371/journal.pgen.1011563 |
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