Occurrence of Internal Parasites and Anthelmintic Resistance in Goats

Extensive anthelmintic (AH) use for endoparasitism prevention, especially gastrointestinal strongyle (GIS) infections, led to AH resistance (AR). This study assessed the internal parasitic profile and AR occurrence in goat herds. Five herds (H, n = 300) raised in household systems in Romania (2020–2...

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Main Authors: Gianluca D’Amico, Adrian-Valentin Potârniche, Bianca-Irina Tucă, Adriana Györke
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Animals
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Online Access:https://www.mdpi.com/2076-2615/15/7/1024
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author Gianluca D’Amico
Adrian-Valentin Potârniche
Bianca-Irina Tucă
Adriana Györke
author_facet Gianluca D’Amico
Adrian-Valentin Potârniche
Bianca-Irina Tucă
Adriana Györke
author_sort Gianluca D’Amico
collection DOAJ
description Extensive anthelmintic (AH) use for endoparasitism prevention, especially gastrointestinal strongyle (GIS) infections, led to AH resistance (AR). This study assessed the internal parasitic profile and AR occurrence in goat herds. Five herds (H, n = 300) raised in household systems in Romania (2020–2021) were dewormed with eprinomectin in the fall (H1, H2) and albendazole in the spring (H3–H5). Fecal samples (n = 67) were collected pre- and 14 days post-AH administration. Coprological examinations, coprocultures, and polymerase chain reaction (PCR) were performed. Anthelmintic resistance was detected in H1, H2, and H5. Pre-AH administrations, <i>Eimeria</i> spp. was the most common parasite (95.5%), followed by GIS (91.0%), <i>P. rufescens</i>/<i>M. capillaris</i> (77.6%), <i>Dyctiocaulus filaria</i> (56.7%), and <i>Moniezia</i> spp. (43.3%). <i>Teladorsagia circumcincta</i> (4/5), <i>Trichostrongylus colubriformis</i> (4/5), <i>Oesophagostomum venulosum</i> (3/5), <i>Haemonchus placei</i> (3/5), <i>Haemonchus contortus</i> (2/5), and <i>Cooperia oncophora</i> (2/5) were identified by PCR. Mean OPG/EPG values for <i>Eimeria</i> spp. and GIS were <1000 eggs/gram feces, tending to be higher in young versus adult goats and in autumn versus spring. FECR (90%CI) values post-AH administration were 38.42 (23.4; 71.8), 54.71 (−4.1; 75.1) for eprinomectin, and 9.78 (−1.7; 64.8) for albendazole, suggesting AH ineffectiveness and AR presence in H1, H2, and H5, respectively. These findings highlight that specific management measures are needed.
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spelling doaj-art-e7bd87b7d0b44805bcc0cd92ec6cfd692025-08-20T02:09:18ZengMDPI AGAnimals2076-26152025-04-01157102410.3390/ani15071024Occurrence of Internal Parasites and Anthelmintic Resistance in GoatsGianluca D’Amico0Adrian-Valentin Potârniche1Bianca-Irina Tucă2Adriana Györke3Department of Parasitology and Parasitic Diseases, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, 400372 Cluj-Napoca, RomaniaDepartment of Infectious Diseases, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, 400372 Cluj-Napoca, RomaniaDepartment of Parasitology and Parasitic Diseases, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, 400372 Cluj-Napoca, RomaniaDepartment of Parasitology and Parasitic Diseases, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, 400372 Cluj-Napoca, RomaniaExtensive anthelmintic (AH) use for endoparasitism prevention, especially gastrointestinal strongyle (GIS) infections, led to AH resistance (AR). This study assessed the internal parasitic profile and AR occurrence in goat herds. Five herds (H, n = 300) raised in household systems in Romania (2020–2021) were dewormed with eprinomectin in the fall (H1, H2) and albendazole in the spring (H3–H5). Fecal samples (n = 67) were collected pre- and 14 days post-AH administration. Coprological examinations, coprocultures, and polymerase chain reaction (PCR) were performed. Anthelmintic resistance was detected in H1, H2, and H5. Pre-AH administrations, <i>Eimeria</i> spp. was the most common parasite (95.5%), followed by GIS (91.0%), <i>P. rufescens</i>/<i>M. capillaris</i> (77.6%), <i>Dyctiocaulus filaria</i> (56.7%), and <i>Moniezia</i> spp. (43.3%). <i>Teladorsagia circumcincta</i> (4/5), <i>Trichostrongylus colubriformis</i> (4/5), <i>Oesophagostomum venulosum</i> (3/5), <i>Haemonchus placei</i> (3/5), <i>Haemonchus contortus</i> (2/5), and <i>Cooperia oncophora</i> (2/5) were identified by PCR. Mean OPG/EPG values for <i>Eimeria</i> spp. and GIS were <1000 eggs/gram feces, tending to be higher in young versus adult goats and in autumn versus spring. FECR (90%CI) values post-AH administration were 38.42 (23.4; 71.8), 54.71 (−4.1; 75.1) for eprinomectin, and 9.78 (−1.7; 64.8) for albendazole, suggesting AH ineffectiveness and AR presence in H1, H2, and H5, respectively. These findings highlight that specific management measures are needed.https://www.mdpi.com/2076-2615/15/7/1024goatsinternal parasitesstrongylesanthelminticsresistancepolymerase chain reaction (PCR)
spellingShingle Gianluca D’Amico
Adrian-Valentin Potârniche
Bianca-Irina Tucă
Adriana Györke
Occurrence of Internal Parasites and Anthelmintic Resistance in Goats
Animals
goats
internal parasites
strongyles
anthelmintics
resistance
polymerase chain reaction (PCR)
title Occurrence of Internal Parasites and Anthelmintic Resistance in Goats
title_full Occurrence of Internal Parasites and Anthelmintic Resistance in Goats
title_fullStr Occurrence of Internal Parasites and Anthelmintic Resistance in Goats
title_full_unstemmed Occurrence of Internal Parasites and Anthelmintic Resistance in Goats
title_short Occurrence of Internal Parasites and Anthelmintic Resistance in Goats
title_sort occurrence of internal parasites and anthelmintic resistance in goats
topic goats
internal parasites
strongyles
anthelmintics
resistance
polymerase chain reaction (PCR)
url https://www.mdpi.com/2076-2615/15/7/1024
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AT adrianvalentinpotarniche occurrenceofinternalparasitesandanthelminticresistanceingoats
AT biancairinatuca occurrenceofinternalparasitesandanthelminticresistanceingoats
AT adrianagyorke occurrenceofinternalparasitesandanthelminticresistanceingoats