Toll-like receptor 8 agonists improve NK-cell function primarily targeting CD56brightCD16− subset

Toll-like receptor 8 agonists improve NK-cell function primarily targeting CD56brightCD16− subset

Background Toll-like receptors (TLRs) are pattern-recognition sensors mainly expressed in innate immune cells that directly recognize conserved pathogen structures (pathogen-associated molecular patterns-PAMPs). Natural killer (NK) cells have been described to express different endosomal TLRs trigge...

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Bibliographic Details
Main Authors: Enrico Maggi, Giovanni Scambia, Anna Fagotti, Lorenzo Moretta, Andrea Pelosi, Irene Veneziani, Valentina D'Oria, Claudia Alicata, Nadine Landolina, Biancamaria Ricci
Format: Article
Language:English
Published: BMJ Publishing Group 2022-01-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/10/1/e003385.full
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