Bilateral Telencephalic Gliomatosis Cerebri in a Dog
An 8-year-old intact male Lagotto Romagnolo was presented with forebrain signs. Neuroanatomic localization was diffuse prosencephalon. MRI revealed diffuse, bilateral, and symmetric T2 and FLAIR hyperintensities in the parieto-occipital white matter and corpus callosum. No mass effect or contrast en...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Veterinary Medicine |
| Online Access: | http://dx.doi.org/10.1155/2014/915808 |
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| _version_ | 1832558625936113664 |
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| author | Mario Ricciardi Antonio De Simone Pasquale Giannuzzi Maria Teresa Mandara Alice Reginato Floriana Gernone |
| author_facet | Mario Ricciardi Antonio De Simone Pasquale Giannuzzi Maria Teresa Mandara Alice Reginato Floriana Gernone |
| author_sort | Mario Ricciardi |
| collection | DOAJ |
| description | An 8-year-old intact male Lagotto Romagnolo was presented with forebrain signs. Neuroanatomic localization was diffuse prosencephalon. MRI revealed diffuse, bilateral, and symmetric T2 and FLAIR hyperintensities in the parieto-occipital white matter and corpus callosum. No mass effect or contrast enhancement was noted. Analysis of cerebrospinal fluid revealed normal protein content and mild mononuclear pleocytosis. Atypical cells were not identified. 15 days later because of the worsening of clinical condition the patient was euthanized upon owner’s request. Neuropathological investigations were consistent with gliomatosis cerebri (GC). Such an unusual imaging pattern appeared similar to some cases of human GC and to a previous reported case in a dog, suggesting a possible repeatable imaging findings for this rare brain neoplasm. GC should be included in the MRI differentials for diffuse bilateral white matter signal changes and specific MRI findings described in this report may help in reaching a presumptive diagnosis of this tumor. |
| format | Article |
| id | doaj-art-e7a5c4e0b6ce4fd9a9646b0d6a648a59 |
| institution | Kabale University |
| issn | 2090-7001 2090-701X |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Veterinary Medicine |
| spelling | doaj-art-e7a5c4e0b6ce4fd9a9646b0d6a648a592025-02-03T01:32:04ZengWileyCase Reports in Veterinary Medicine2090-70012090-701X2014-01-01201410.1155/2014/915808915808Bilateral Telencephalic Gliomatosis Cerebri in a DogMario Ricciardi0Antonio De Simone1Pasquale Giannuzzi2Maria Teresa Mandara3Alice Reginato4Floriana Gernone5“Pingry” Veterinary Hospital, Via Medaglie d’Oro 5, 70126 Bari, Italy“Pingry” Veterinary Hospital, Via Medaglie d’Oro 5, 70126 Bari, Italy“Pingry” Veterinary Hospital, Via Medaglie d’Oro 5, 70126 Bari, ItalyDepartment of Biopathological Science and Hygiene of Food and Animal Productions, Faculty of Veterinary Medicine, University of Perugia, 06126 Perugia, ItalyDepartment of Biopathological Science and Hygiene of Food and Animal Productions, Faculty of Veterinary Medicine, University of Perugia, 06126 Perugia, Italy“Pingry” Veterinary Hospital, Via Medaglie d’Oro 5, 70126 Bari, ItalyAn 8-year-old intact male Lagotto Romagnolo was presented with forebrain signs. Neuroanatomic localization was diffuse prosencephalon. MRI revealed diffuse, bilateral, and symmetric T2 and FLAIR hyperintensities in the parieto-occipital white matter and corpus callosum. No mass effect or contrast enhancement was noted. Analysis of cerebrospinal fluid revealed normal protein content and mild mononuclear pleocytosis. Atypical cells were not identified. 15 days later because of the worsening of clinical condition the patient was euthanized upon owner’s request. Neuropathological investigations were consistent with gliomatosis cerebri (GC). Such an unusual imaging pattern appeared similar to some cases of human GC and to a previous reported case in a dog, suggesting a possible repeatable imaging findings for this rare brain neoplasm. GC should be included in the MRI differentials for diffuse bilateral white matter signal changes and specific MRI findings described in this report may help in reaching a presumptive diagnosis of this tumor.http://dx.doi.org/10.1155/2014/915808 |
| spellingShingle | Mario Ricciardi Antonio De Simone Pasquale Giannuzzi Maria Teresa Mandara Alice Reginato Floriana Gernone Bilateral Telencephalic Gliomatosis Cerebri in a Dog Case Reports in Veterinary Medicine |
| title | Bilateral Telencephalic Gliomatosis Cerebri in a Dog |
| title_full | Bilateral Telencephalic Gliomatosis Cerebri in a Dog |
| title_fullStr | Bilateral Telencephalic Gliomatosis Cerebri in a Dog |
| title_full_unstemmed | Bilateral Telencephalic Gliomatosis Cerebri in a Dog |
| title_short | Bilateral Telencephalic Gliomatosis Cerebri in a Dog |
| title_sort | bilateral telencephalic gliomatosis cerebri in a dog |
| url | http://dx.doi.org/10.1155/2014/915808 |
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