SARS-CoV-2 S-protein expression drives syncytia formation in endothelial cells

Abstract SARS-CoV-2 is a viral infection, best studied in the context of epithelial cell infection. Epithelial cells, when infected with SARS-CoV-2 express the viral S-protein, which causes host cells to fuse together into large multi-nucleated cells known as syncytia. Because SARS-CoV-2 infections...

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Bibliographic Details
Main Authors: Katie V. Tieu, Madaline Espey, Aarthi Narayanan, Rebecca L. Heise, Farhang Alem, Daniel E. Conway
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-86242-1
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