Effects of a New Nano-Silver Fluoride-Containing Dentifrice on Demineralization of Enamel and Streptococcus mutans Adhesion and Acidogenicity
An experimental dentifrice containing nano-silver fluoride (NSF) and a sodium fluoride (NaF) toothpaste were tested in vitro, against S. mutans, to evaluate the minimal inhibitory concentration (MIC), minimal bactericidal concentration (MBC), antiadherence, antiacid, enamel microhardness, and OCT. T...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | International Journal of Dentistry |
| Online Access: | http://dx.doi.org/10.1155/2018/1351925 |
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| author | Joás Araújo Teixeira Amitis Vieira Costa e Silva Valdeci Elias dos Santos Júnior Paulo Correia de Melo Júnior Manuela Arnaud Maria Goretti Lima Miguel Angel Pelagio Flores Thayza Christina Montenegro Stamford José Ricardo Dias Pereira Andréa Gadelha Ribeiro Targino André Galembeck Aronita Rosenblatt |
| author_facet | Joás Araújo Teixeira Amitis Vieira Costa e Silva Valdeci Elias dos Santos Júnior Paulo Correia de Melo Júnior Manuela Arnaud Maria Goretti Lima Miguel Angel Pelagio Flores Thayza Christina Montenegro Stamford José Ricardo Dias Pereira Andréa Gadelha Ribeiro Targino André Galembeck Aronita Rosenblatt |
| author_sort | Joás Araújo Teixeira |
| collection | DOAJ |
| description | An experimental dentifrice containing nano-silver fluoride (NSF) and a sodium fluoride (NaF) toothpaste were tested in vitro, against S. mutans, to evaluate the minimal inhibitory concentration (MIC), minimal bactericidal concentration (MBC), antiadherence, antiacid, enamel microhardness, and OCT. The microdilution technique was used to determine the MIC and MBC. Fragments of deciduous enamel were treated with dentifrice slurries, containing bacterial suspension and PBS-treated saliva. The quantification of the microorganisms that adhered to the enamel was determined after 24 hours of incubation, and media pH readings were performed after 2 hours and 24 hours. Deciduous teeth were evaluated for microhardness and OCT during 14 days of pH cycling. Data were statistically analyzed using Student’s t-test, Mann–Whitney U test, ANOVA, and Tukey tests at 5% of significance. Dentifrices containing NSF presented a lower MIC and higher statistically significant results compared to NaF dentifrices with respect to preventing bacterial adhesion and pH decreases. NSF and NaF dentifrices showed the same ability to avoid enamel demineralization corroborated by the OCT images. The NSF formulation had a better antibacterial effect compared to NaF dentifrices and similar action on the demineralization of enamel indicating their potential effectiveness to prevent caries. |
| format | Article |
| id | doaj-art-e79025d812264705a4fcb013ca6a6f7c |
| institution | Kabale University |
| issn | 1687-8728 1687-8736 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Dentistry |
| spelling | doaj-art-e79025d812264705a4fcb013ca6a6f7c2025-02-03T05:45:35ZengWileyInternational Journal of Dentistry1687-87281687-87362018-01-01201810.1155/2018/13519251351925Effects of a New Nano-Silver Fluoride-Containing Dentifrice on Demineralization of Enamel and Streptococcus mutans Adhesion and AcidogenicityJoás Araújo Teixeira0Amitis Vieira Costa e Silva1Valdeci Elias dos Santos Júnior2Paulo Correia de Melo Júnior3Manuela Arnaud4Maria Goretti Lima5Miguel Angel Pelagio Flores6Thayza Christina Montenegro Stamford7José Ricardo Dias Pereira8Andréa Gadelha Ribeiro Targino9André Galembeck10Aronita Rosenblatt11Faculty of Dentistry, University of Pernambuco, No. 1650 Av. Gal. Newton Cavalcanti, 54756-020 Camaragibe, PE, BrazilFaculty of Dentistry, University of Pernambuco, No. 1650 Av. Gal. Newton Cavalcanti, 54756-020 Camaragibe, PE, BrazilFaculty of Dentistry, University of Pernambuco, No. 1650 Av. Gal. Newton Cavalcanti, 54756-020 Camaragibe, PE, BrazilFaculty of Dentistry, University of Pernambuco, No. 1650 Av. Gal. Newton Cavalcanti, 54756-020 Camaragibe, PE, BrazilFaculty of Dentistry, University of Pernambuco, No. 1650 Av. Gal. Newton Cavalcanti, 54756-020 Camaragibe, PE, BrazilFaculty of Dentistry, University of Pernambuco, No. 1650 Av. Gal. Newton Cavalcanti, 54756-020 Camaragibe, PE, BrazilCenter of Strategic Technologies of Northeast, Campus MCTI Nordeste, No. 01 Av. Prof. Luiz Freire, 50740-540 Recife, PE, BrazilFederal University of Pernambuco, Cidade Universitária, No. 1235 Av. Prof. Morais Rego, CEP 50670-901 Recife, PE, BrazilFederal University of Pernambuco, Cidade Universitária, No. 1235 Av. Prof. Morais Rego, CEP 50670-901 Recife, PE, BrazilDepartment of Dentistry, Universidade Federal da Paraiba, 50670-901 João Pessoa, PB, BrazilCenter of Strategic Technologies of Northeast, Campus MCTI Nordeste, No. 01 Av. Prof. Luiz Freire, 50740-540 Recife, PE, BrazilFaculty of Dentistry, University of Pernambuco, No. 1650 Av. Gal. Newton Cavalcanti, 54756-020 Camaragibe, PE, BrazilAn experimental dentifrice containing nano-silver fluoride (NSF) and a sodium fluoride (NaF) toothpaste were tested in vitro, against S. mutans, to evaluate the minimal inhibitory concentration (MIC), minimal bactericidal concentration (MBC), antiadherence, antiacid, enamel microhardness, and OCT. The microdilution technique was used to determine the MIC and MBC. Fragments of deciduous enamel were treated with dentifrice slurries, containing bacterial suspension and PBS-treated saliva. The quantification of the microorganisms that adhered to the enamel was determined after 24 hours of incubation, and media pH readings were performed after 2 hours and 24 hours. Deciduous teeth were evaluated for microhardness and OCT during 14 days of pH cycling. Data were statistically analyzed using Student’s t-test, Mann–Whitney U test, ANOVA, and Tukey tests at 5% of significance. Dentifrices containing NSF presented a lower MIC and higher statistically significant results compared to NaF dentifrices with respect to preventing bacterial adhesion and pH decreases. NSF and NaF dentifrices showed the same ability to avoid enamel demineralization corroborated by the OCT images. The NSF formulation had a better antibacterial effect compared to NaF dentifrices and similar action on the demineralization of enamel indicating their potential effectiveness to prevent caries.http://dx.doi.org/10.1155/2018/1351925 |
| spellingShingle | Joás Araújo Teixeira Amitis Vieira Costa e Silva Valdeci Elias dos Santos Júnior Paulo Correia de Melo Júnior Manuela Arnaud Maria Goretti Lima Miguel Angel Pelagio Flores Thayza Christina Montenegro Stamford José Ricardo Dias Pereira Andréa Gadelha Ribeiro Targino André Galembeck Aronita Rosenblatt Effects of a New Nano-Silver Fluoride-Containing Dentifrice on Demineralization of Enamel and Streptococcus mutans Adhesion and Acidogenicity International Journal of Dentistry |
| title | Effects of a New Nano-Silver Fluoride-Containing Dentifrice on Demineralization of Enamel and Streptococcus mutans Adhesion and Acidogenicity |
| title_full | Effects of a New Nano-Silver Fluoride-Containing Dentifrice on Demineralization of Enamel and Streptococcus mutans Adhesion and Acidogenicity |
| title_fullStr | Effects of a New Nano-Silver Fluoride-Containing Dentifrice on Demineralization of Enamel and Streptococcus mutans Adhesion and Acidogenicity |
| title_full_unstemmed | Effects of a New Nano-Silver Fluoride-Containing Dentifrice on Demineralization of Enamel and Streptococcus mutans Adhesion and Acidogenicity |
| title_short | Effects of a New Nano-Silver Fluoride-Containing Dentifrice on Demineralization of Enamel and Streptococcus mutans Adhesion and Acidogenicity |
| title_sort | effects of a new nano silver fluoride containing dentifrice on demineralization of enamel and streptococcus mutans adhesion and acidogenicity |
| url | http://dx.doi.org/10.1155/2018/1351925 |
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