The Effects of Exercise in Hypoxia and Normoxia Conditions on Endothelin-1 and EPO in Endurance Runners

Purpose: The purpose of this study was to determine the effects ‘‘living high, training high and low’’ (LHTLH) protocol on serum endothelin-1 and erythropoietin protein levels and 5000 m performance Iranian national team endurance runners. Method: Eight male runners (age of 24.4±3.1 years, height of...

Full description

Saved in:
Bibliographic Details
Main Author: Roohollah Mohammadi Mirzaei
Format: Article
Language:English
Published: Allameh Tabataba'i University Press 2020-07-01
Series:New Approaches in Sport Sciences
Subjects:
Online Access:http://nass.atu.ac.ir/article_11251_2ca822e362510aa1d820446cc2e21d56.pdf
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850230402809069568
author Roohollah Mohammadi Mirzaei
author_facet Roohollah Mohammadi Mirzaei
author_sort Roohollah Mohammadi Mirzaei
collection DOAJ
description Purpose: The purpose of this study was to determine the effects ‘‘living high, training high and low’’ (LHTLH) protocol on serum endothelin-1 and erythropoietin protein levels and 5000 m performance Iranian national team endurance runners. Method: Eight male runners (age of 24.4±3.1 years, height of 180.5±4.2 cm, weight of 66.7±3.4 kg, BMI of 20.1±5.0 kg/m2) voluntary participated in this research along with dedicated exercises with the running at middle distance to marathon method in high and low altitudes. 5000 m test accomplished for all study cases and blood samples were taken before and 24 hours after that. The exercises were including continues, interval, aerobic and resistance trainings. Runners were planned to have sixteen training session per week on at long time for 11 weeks live high-train high and low altitude participate in period training. Results: Data were collected and analyzed by analysis of variance with repeated measures (P≤0.05). 5000 m running time significantly decreased related to time effect before and after training. No significant changes were observed in EPO (P≥0.05). But endothelin-1 was significantly increased before to after training protocol (P≤0.05). Conclusions: In this study showed that specific training program decreases 5000 m running time in lower altitude not because of its direct effect on EPO Level changes but hematological and metabolism changes and increase endothelin-1 levels might to be the real cause performance improve of that in hypoxic and normoxia condition.
format Article
id doaj-art-e77e1bbaff5d4fb38ee36df95516c4a5
institution OA Journals
issn 2588-6614
language English
publishDate 2020-07-01
publisher Allameh Tabataba'i University Press
record_format Article
series New Approaches in Sport Sciences
spelling doaj-art-e77e1bbaff5d4fb38ee36df95516c4a52025-08-20T02:03:53ZengAllameh Tabataba'i University PressNew Approaches in Sport Sciences2588-66142020-07-012314516210.22054/NASS.2020.53272.1065The Effects of Exercise in Hypoxia and Normoxia Conditions on Endothelin-1 and EPO in Endurance RunnersRoohollah Mohammadi Mirzaei 0Assistant professor, faculty of physical education and sport sciences, farhangian university, Tehran, IranPurpose: The purpose of this study was to determine the effects ‘‘living high, training high and low’’ (LHTLH) protocol on serum endothelin-1 and erythropoietin protein levels and 5000 m performance Iranian national team endurance runners. Method: Eight male runners (age of 24.4±3.1 years, height of 180.5±4.2 cm, weight of 66.7±3.4 kg, BMI of 20.1±5.0 kg/m2) voluntary participated in this research along with dedicated exercises with the running at middle distance to marathon method in high and low altitudes. 5000 m test accomplished for all study cases and blood samples were taken before and 24 hours after that. The exercises were including continues, interval, aerobic and resistance trainings. Runners were planned to have sixteen training session per week on at long time for 11 weeks live high-train high and low altitude participate in period training. Results: Data were collected and analyzed by analysis of variance with repeated measures (P≤0.05). 5000 m running time significantly decreased related to time effect before and after training. No significant changes were observed in EPO (P≥0.05). But endothelin-1 was significantly increased before to after training protocol (P≤0.05). Conclusions: In this study showed that specific training program decreases 5000 m running time in lower altitude not because of its direct effect on EPO Level changes but hematological and metabolism changes and increase endothelin-1 levels might to be the real cause performance improve of that in hypoxic and normoxia condition.http://nass.atu.ac.ir/article_11251_2ca822e362510aa1d820446cc2e21d56.pdfepo endothelin-1 endurance runners hypoxia normoxia
spellingShingle Roohollah Mohammadi Mirzaei
The Effects of Exercise in Hypoxia and Normoxia Conditions on Endothelin-1 and EPO in Endurance Runners
New Approaches in Sport Sciences
epo endothelin-1 endurance runners hypoxia normoxia
title The Effects of Exercise in Hypoxia and Normoxia Conditions on Endothelin-1 and EPO in Endurance Runners
title_full The Effects of Exercise in Hypoxia and Normoxia Conditions on Endothelin-1 and EPO in Endurance Runners
title_fullStr The Effects of Exercise in Hypoxia and Normoxia Conditions on Endothelin-1 and EPO in Endurance Runners
title_full_unstemmed The Effects of Exercise in Hypoxia and Normoxia Conditions on Endothelin-1 and EPO in Endurance Runners
title_short The Effects of Exercise in Hypoxia and Normoxia Conditions on Endothelin-1 and EPO in Endurance Runners
title_sort effects of exercise in hypoxia and normoxia conditions on endothelin 1 and epo in endurance runners
topic epo endothelin-1 endurance runners hypoxia normoxia
url http://nass.atu.ac.ir/article_11251_2ca822e362510aa1d820446cc2e21d56.pdf
work_keys_str_mv AT roohollahmohammadimirzaei theeffectsofexerciseinhypoxiaandnormoxiaconditionsonendothelin1andepoinendurancerunners
AT roohollahmohammadimirzaei effectsofexerciseinhypoxiaandnormoxiaconditionsonendothelin1andepoinendurancerunners