Mucin 18‐targeted humanized monoclonal antibody immune positron emission tomography imaging and patient‐derived tumor xenograft visualization

Mucin 18‐targeted humanized monoclonal antibody immune positron emission tomography imaging and patient‐derived tumor xenograft visualization

Abstract In the context of precision diagnosis for various subtypes of melanoma, identifying biomarkers with clinical translational potential from a molecular standpoint is crucial for a more comprehensive characterization of the disease. Mucin 18 (MUC18) is highly expressed in both tumor cells and...

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Main Authors: Qian Zhang, Haizhen Du, Xiuli Ma, Song Liu, Xiangxing Kong, Muye Hu, Jing Shi, Yanfang Tang, ShuHui Liu, Xun Meng, Qian Guo, Yan Kong, Jun Guo, Bin Lian, Zhi Yang, Hua Zhu
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:View
Subjects:
humanized mAb
immuno‐PET imaging
melanoma
PDX model
Online Access:https://doi.org/10.1002/VIW.20240055
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