A Rare Presentation of Whitmore’s Disease (Melioidosis) with Multisystem Abscess in a Diabetic Patient with Intractable Hiccups
Whitmore’s disease (Melioidosis) is caused by Burkholderia pseudomallei (B. pseudomallei), a gram-negative bacterium with high pathogenicity. The disease manifests in various forms, ranging from pneumonia or localised abscesses to acute septicaemia or arthritis. Culture and sensitivity tests are the...
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JCDR Research and Publications Private Limited
2025-04-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/20923/76258_CE[Ra1]_F(SHU)_QC(PS_SS)_PF1(AG_SL)_PFA(IS)_PB(AG_IS)_PN(IS).pdf |
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| author | Vuppala Rachana Vignessh Raveekumaran |
| author_facet | Vuppala Rachana Vignessh Raveekumaran |
| author_sort | Vuppala Rachana |
| collection | DOAJ |
| description | Whitmore’s disease (Melioidosis) is caused by Burkholderia pseudomallei (B. pseudomallei), a gram-negative bacterium with high pathogenicity. The disease manifests in various forms, ranging from pneumonia or localised abscesses to acute septicaemia or arthritis. Culture and sensitivity tests are the gold standards for diagnosis. For treatment, ceftazidime or meropenem is recommended during the intensive phase (10-14 days), while oral co-trimoxazole is the drug of choice for the eradication phase (3-6 months). Surgical drainage of abscesses plays an important role in the management of melioidosis. However, the occurrence of multisystem abscesses is very rare. Hereby, authors report a case of a 63-year-old female with a known history of diabetes who presented with fever and hiccups for 40 days, deranged liver function tests, and leukocytosis. A Computed Tomography (CT) scan revealed lung and liver abscesses, and the culture yielded B. pseudomallei. The patient was diagnosed with melioidosis, treated with antibiotics, and subsequently discharged. |
| format | Article |
| id | doaj-art-e76ca2b2c22a47839b4d24d9b204764d |
| institution | DOAJ |
| issn | 2249-782X 0973-709X |
| language | English |
| publishDate | 2025-04-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj-art-e76ca2b2c22a47839b4d24d9b204764d2025-08-20T03:10:42ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2025-04-01194OD22OD2410.7860/JCDR/2025/76258.20923A Rare Presentation of Whitmore’s Disease (Melioidosis) with Multisystem Abscess in a Diabetic Patient with Intractable HiccupsVuppala Rachana0Vignessh Raveekumaran1https://orcid.org/0009-0006-6283-6542Resident, Department of General Medicine, Mahatma Gandhi Medical College and Research Institute, SBVU (Deemed to be University), Pondicherry, India.Assistant Professor, Department of General Medicine, Mahatma Gandhi Medical College and Research Institute, SBVU (Deemed to be University), Pondicherry, India.Whitmore’s disease (Melioidosis) is caused by Burkholderia pseudomallei (B. pseudomallei), a gram-negative bacterium with high pathogenicity. The disease manifests in various forms, ranging from pneumonia or localised abscesses to acute septicaemia or arthritis. Culture and sensitivity tests are the gold standards for diagnosis. For treatment, ceftazidime or meropenem is recommended during the intensive phase (10-14 days), while oral co-trimoxazole is the drug of choice for the eradication phase (3-6 months). Surgical drainage of abscesses plays an important role in the management of melioidosis. However, the occurrence of multisystem abscesses is very rare. Hereby, authors report a case of a 63-year-old female with a known history of diabetes who presented with fever and hiccups for 40 days, deranged liver function tests, and leukocytosis. A Computed Tomography (CT) scan revealed lung and liver abscesses, and the culture yielded B. pseudomallei. The patient was diagnosed with melioidosis, treated with antibiotics, and subsequently discharged.https://jcdr.net/articles/PDF/20923/76258_CE[Ra1]_F(SHU)_QC(PS_SS)_PF1(AG_SL)_PFA(IS)_PB(AG_IS)_PN(IS).pdfburkholderia pseudomalleidiabetes mellitusmeropenemmultiple abscess |
| spellingShingle | Vuppala Rachana Vignessh Raveekumaran A Rare Presentation of Whitmore’s Disease (Melioidosis) with Multisystem Abscess in a Diabetic Patient with Intractable Hiccups Journal of Clinical and Diagnostic Research burkholderia pseudomallei diabetes mellitus meropenem multiple abscess |
| title | A Rare Presentation of Whitmore’s Disease (Melioidosis) with Multisystem Abscess in a Diabetic Patient with Intractable Hiccups |
| title_full | A Rare Presentation of Whitmore’s Disease (Melioidosis) with Multisystem Abscess in a Diabetic Patient with Intractable Hiccups |
| title_fullStr | A Rare Presentation of Whitmore’s Disease (Melioidosis) with Multisystem Abscess in a Diabetic Patient with Intractable Hiccups |
| title_full_unstemmed | A Rare Presentation of Whitmore’s Disease (Melioidosis) with Multisystem Abscess in a Diabetic Patient with Intractable Hiccups |
| title_short | A Rare Presentation of Whitmore’s Disease (Melioidosis) with Multisystem Abscess in a Diabetic Patient with Intractable Hiccups |
| title_sort | rare presentation of whitmore s disease melioidosis with multisystem abscess in a diabetic patient with intractable hiccups |
| topic | burkholderia pseudomallei diabetes mellitus meropenem multiple abscess |
| url | https://jcdr.net/articles/PDF/20923/76258_CE[Ra1]_F(SHU)_QC(PS_SS)_PF1(AG_SL)_PFA(IS)_PB(AG_IS)_PN(IS).pdf |
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