Green Synthesis of AgNPs and Fe2O3NPs Using Garlic Plant and Study their Anticancer Activity against Cervical Cancer Cells
In this study, silver and iron nanoparticles were biosynthesized using the garlic plant, an economical and environmentally friendly method. A blend of chitosan (CS) and polyvinylalcohol (PVA) was prepared. The silver nanoparticles (AgNPs), iron oxide nanoparticles (Fe2O3NPs), and the (CS/PVA) blend...
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| Format: | Article |
| Language: | English |
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University of Baghdad
2024-06-01
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| Series: | Iraqi Journal of Physics |
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| Online Access: | https://ijp.uobaghdad.edu.iq/index.php/physics/article/view/1144 |
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| author | Hala H. Ali Farah T. Mohammed Noori |
| author_facet | Hala H. Ali Farah T. Mohammed Noori |
| author_sort | Hala H. Ali |
| collection | DOAJ |
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In this study, silver and iron nanoparticles were biosynthesized using the garlic plant, an economical and environmentally friendly method. A blend of chitosan (CS) and polyvinylalcohol (PVA) was prepared. The silver nanoparticles (AgNPs), iron oxide nanoparticles (Fe2O3NPs), and the (CS/PVA) blend were characterized by X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), and Field Emission Scanning Electron Microscopy (FE-SEM) analyses. The FE-SEM images revealed that Fe2O3NPs were cubical and hexagonal, and AgNPs were spherical aggregates. AgNPs with blend (CS/PVA) and Fe2O3NPs with blend (CS/PVA) and (Fe2O3NPs/blend (CS/PVA) /AgNPs) composite were synthesized and tested for anticancer activity against cervical cancer cells (Hela) using the MTT assay. Best kills and the highest inhibitory effect were observed in (AgNPs/blend (CS/PVA)) and (Fe2O3NPs/Blend (CS/PVA)/AgNPs) composite. These findings demonstrated the method's ability to synthesize nanocomposites with desirable physical, chemical and biological properties. Therefore, these findings demonstrate the new antibacterial and robust cytotoxicity features of the nanocomposite material, which has promising medical applications.
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| format | Article |
| id | doaj-art-e7657703809d4e0bb4e421b7c37ea977 |
| institution | OA Journals |
| issn | 2070-4003 2664-5548 |
| language | English |
| publishDate | 2024-06-01 |
| publisher | University of Baghdad |
| record_format | Article |
| series | Iraqi Journal of Physics |
| spelling | doaj-art-e7657703809d4e0bb4e421b7c37ea9772025-08-20T01:57:40ZengUniversity of BaghdadIraqi Journal of Physics2070-40032664-55482024-06-0122210.30723/ijp.v22i2.1144Green Synthesis of AgNPs and Fe2O3NPs Using Garlic Plant and Study their Anticancer Activity against Cervical Cancer CellsHala H. Ali0Farah T. Mohammed Noori1Department of Physics, College of Science, University of Baghdad, Baghdad, IraqDepartment of Physics, College of Science, University of Baghdad, Baghdad, Iraq In this study, silver and iron nanoparticles were biosynthesized using the garlic plant, an economical and environmentally friendly method. A blend of chitosan (CS) and polyvinylalcohol (PVA) was prepared. The silver nanoparticles (AgNPs), iron oxide nanoparticles (Fe2O3NPs), and the (CS/PVA) blend were characterized by X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), and Field Emission Scanning Electron Microscopy (FE-SEM) analyses. The FE-SEM images revealed that Fe2O3NPs were cubical and hexagonal, and AgNPs were spherical aggregates. AgNPs with blend (CS/PVA) and Fe2O3NPs with blend (CS/PVA) and (Fe2O3NPs/blend (CS/PVA) /AgNPs) composite were synthesized and tested for anticancer activity against cervical cancer cells (Hela) using the MTT assay. Best kills and the highest inhibitory effect were observed in (AgNPs/blend (CS/PVA)) and (Fe2O3NPs/Blend (CS/PVA)/AgNPs) composite. These findings demonstrated the method's ability to synthesize nanocomposites with desirable physical, chemical and biological properties. Therefore, these findings demonstrate the new antibacterial and robust cytotoxicity features of the nanocomposite material, which has promising medical applications. https://ijp.uobaghdad.edu.iq/index.php/physics/article/view/1144BiosynthesisGreen synthesisNano materialCervical cancer(Hela)Cytotoxicity. |
| spellingShingle | Hala H. Ali Farah T. Mohammed Noori Green Synthesis of AgNPs and Fe2O3NPs Using Garlic Plant and Study their Anticancer Activity against Cervical Cancer Cells Iraqi Journal of Physics Biosynthesis Green synthesis Nano material Cervical cancer(Hela) Cytotoxicity. |
| title | Green Synthesis of AgNPs and Fe2O3NPs Using Garlic Plant and Study their Anticancer Activity against Cervical Cancer Cells |
| title_full | Green Synthesis of AgNPs and Fe2O3NPs Using Garlic Plant and Study their Anticancer Activity against Cervical Cancer Cells |
| title_fullStr | Green Synthesis of AgNPs and Fe2O3NPs Using Garlic Plant and Study their Anticancer Activity against Cervical Cancer Cells |
| title_full_unstemmed | Green Synthesis of AgNPs and Fe2O3NPs Using Garlic Plant and Study their Anticancer Activity against Cervical Cancer Cells |
| title_short | Green Synthesis of AgNPs and Fe2O3NPs Using Garlic Plant and Study their Anticancer Activity against Cervical Cancer Cells |
| title_sort | green synthesis of agnps and fe2o3nps using garlic plant and study their anticancer activity against cervical cancer cells |
| topic | Biosynthesis Green synthesis Nano material Cervical cancer(Hela) Cytotoxicity. |
| url | https://ijp.uobaghdad.edu.iq/index.php/physics/article/view/1144 |
| work_keys_str_mv | AT halahali greensynthesisofagnpsandfe2o3npsusinggarlicplantandstudytheiranticanceractivityagainstcervicalcancercells AT farahtmohammednoori greensynthesisofagnpsandfe2o3npsusinggarlicplantandstudytheiranticanceractivityagainstcervicalcancercells |