Hypoxia: An Unusual Cause with Specific Treatment

Hypoxia is a well-recognized consequence of venous admixture resulting from right to left intracardiac shunting. Right to left shunting is usually associated with high pulmonary artery pressure or alteration in the direction of blood flow due to an anatomical abnormality of the thorax. Surgical or p...

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Main Authors: John P. Berger, Ganesh Raveendran, David H. Ingbar, Maneesh Bhargava
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Pulmonology
Online Access:http://dx.doi.org/10.1155/2015/956341
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author John P. Berger
Ganesh Raveendran
David H. Ingbar
Maneesh Bhargava
author_facet John P. Berger
Ganesh Raveendran
David H. Ingbar
Maneesh Bhargava
author_sort John P. Berger
collection DOAJ
description Hypoxia is a well-recognized consequence of venous admixture resulting from right to left intracardiac shunting. Right to left shunting is usually associated with high pulmonary artery pressure or alteration in the direction of blood flow due to an anatomical abnormality of the thorax. Surgical or percutaneous closure remains controversial; however it is performed frequently for patients presenting with clinical sequela presumed to be resulting from paradoxical embolization secondary to right to left shunting. We report two patients with hypoxia and dyspnea due to right to left shunting through a patent foramen ovale (PFO) and venous admixture in the absence of elevated pulmonary artery pressures or other predisposing conditions like pneumonectomy or diaphragmatic weakness. Percutaneous closures of the PFOs with the self-centering Amplatzer device resulted in resolution of hypoxia and symptoms related to it.
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spelling doaj-art-e765232be2de4e27bc9f792cbda9ef242025-08-20T03:26:10ZengWileyCase Reports in Pulmonology2090-68462090-68542015-01-01201510.1155/2015/956341956341Hypoxia: An Unusual Cause with Specific TreatmentJohn P. Berger0Ganesh Raveendran1David H. Ingbar2Maneesh Bhargava3Division of Pulmonary, Allergy, Critical Care and Sleep Medicine and Division of Cardiology, Department of Medicine, University of Minnesota, MN 55455, USADivision of Pulmonary, Allergy, Critical Care and Sleep Medicine and Division of Cardiology, Department of Medicine, University of Minnesota, MN 55455, USADivision of Pulmonary, Allergy, Critical Care and Sleep Medicine and Division of Cardiology, Department of Medicine, University of Minnesota, MN 55455, USADivision of Pulmonary, Allergy, Critical Care and Sleep Medicine and Division of Cardiology, Department of Medicine, University of Minnesota, MN 55455, USAHypoxia is a well-recognized consequence of venous admixture resulting from right to left intracardiac shunting. Right to left shunting is usually associated with high pulmonary artery pressure or alteration in the direction of blood flow due to an anatomical abnormality of the thorax. Surgical or percutaneous closure remains controversial; however it is performed frequently for patients presenting with clinical sequela presumed to be resulting from paradoxical embolization secondary to right to left shunting. We report two patients with hypoxia and dyspnea due to right to left shunting through a patent foramen ovale (PFO) and venous admixture in the absence of elevated pulmonary artery pressures or other predisposing conditions like pneumonectomy or diaphragmatic weakness. Percutaneous closures of the PFOs with the self-centering Amplatzer device resulted in resolution of hypoxia and symptoms related to it.http://dx.doi.org/10.1155/2015/956341
spellingShingle John P. Berger
Ganesh Raveendran
David H. Ingbar
Maneesh Bhargava
Hypoxia: An Unusual Cause with Specific Treatment
Case Reports in Pulmonology
title Hypoxia: An Unusual Cause with Specific Treatment
title_full Hypoxia: An Unusual Cause with Specific Treatment
title_fullStr Hypoxia: An Unusual Cause with Specific Treatment
title_full_unstemmed Hypoxia: An Unusual Cause with Specific Treatment
title_short Hypoxia: An Unusual Cause with Specific Treatment
title_sort hypoxia an unusual cause with specific treatment
url http://dx.doi.org/10.1155/2015/956341
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AT ganeshraveendran hypoxiaanunusualcausewithspecifictreatment
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AT maneeshbhargava hypoxiaanunusualcausewithspecifictreatment