Nutritional Manipulation of One-Carbon Metabolism: Effects on Arsenic Methylation and Toxicity
Exposure to arsenic (As) through drinking water is a substantial problem worldwide. The methylation of As, a reactive metalloid, generates monomethyl- (MMA) and dimethyl-arsenical (DMA) species. The biochemical pathway that catalyzes these reactions, one-carbon metabolism, is regulated by folate and...
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| Main Authors: | Megan N. Hall, Mary V. Gamble |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2012-01-01
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| Series: | Journal of Toxicology |
| Online Access: | http://dx.doi.org/10.1155/2012/595307 |
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