The Unmasking Effect: Propofol-Induced Brugada Pattern in a Critically Ill Patient

Brugada syndrome is a known cause of dysrhythmias and sudden cardiac death. It is linked to mutations in myocardial sodium channel leading to hyperexcitable cardiac myocytes. The use of this sedative has been linked to the development of inducible Brugada via blockade of sodium currents in cardiac m...

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Main Authors: Esiemoghie Akhigbe, Ebubechukwu Ezeh, Benjamin Dao, Kelechukwu Okoro, Paul Okhumale
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Case Reports in Cardiology
Online Access:http://dx.doi.org/10.1155/2022/9226861
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author Esiemoghie Akhigbe
Ebubechukwu Ezeh
Benjamin Dao
Kelechukwu Okoro
Paul Okhumale
author_facet Esiemoghie Akhigbe
Ebubechukwu Ezeh
Benjamin Dao
Kelechukwu Okoro
Paul Okhumale
author_sort Esiemoghie Akhigbe
collection DOAJ
description Brugada syndrome is a known cause of dysrhythmias and sudden cardiac death. It is linked to mutations in myocardial sodium channel leading to hyperexcitable cardiac myocytes. The use of this sedative has been linked to the development of inducible Brugada via blockade of sodium currents in cardiac myocytes. Although propofol is usually avoided in patients with known Brugada syndrome, some patients might have undiagnosed Brugada syndrome and thus are at risk for complications. We present a case of propofol induced Brugada in a critically ill patient.
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institution Kabale University
issn 2090-6412
language English
publishDate 2022-01-01
publisher Wiley
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series Case Reports in Cardiology
spelling doaj-art-e73c82622298467a909eb0ff6664e1df2025-02-03T05:53:29ZengWileyCase Reports in Cardiology2090-64122022-01-01202210.1155/2022/9226861The Unmasking Effect: Propofol-Induced Brugada Pattern in a Critically Ill PatientEsiemoghie Akhigbe0Ebubechukwu Ezeh1Benjamin Dao2Kelechukwu Okoro3Paul Okhumale4Department of Internal MedicineDepartment of Internal MedicineDepartment of Cardiovascular ServicesDepartment of Cardiovascular ServicesDepartment of Cardiovascular ServicesBrugada syndrome is a known cause of dysrhythmias and sudden cardiac death. It is linked to mutations in myocardial sodium channel leading to hyperexcitable cardiac myocytes. The use of this sedative has been linked to the development of inducible Brugada via blockade of sodium currents in cardiac myocytes. Although propofol is usually avoided in patients with known Brugada syndrome, some patients might have undiagnosed Brugada syndrome and thus are at risk for complications. We present a case of propofol induced Brugada in a critically ill patient.http://dx.doi.org/10.1155/2022/9226861
spellingShingle Esiemoghie Akhigbe
Ebubechukwu Ezeh
Benjamin Dao
Kelechukwu Okoro
Paul Okhumale
The Unmasking Effect: Propofol-Induced Brugada Pattern in a Critically Ill Patient
Case Reports in Cardiology
title The Unmasking Effect: Propofol-Induced Brugada Pattern in a Critically Ill Patient
title_full The Unmasking Effect: Propofol-Induced Brugada Pattern in a Critically Ill Patient
title_fullStr The Unmasking Effect: Propofol-Induced Brugada Pattern in a Critically Ill Patient
title_full_unstemmed The Unmasking Effect: Propofol-Induced Brugada Pattern in a Critically Ill Patient
title_short The Unmasking Effect: Propofol-Induced Brugada Pattern in a Critically Ill Patient
title_sort unmasking effect propofol induced brugada pattern in a critically ill patient
url http://dx.doi.org/10.1155/2022/9226861
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