Effects of Elevated Ambient Temperature on Reproductive Outcomes and Offspring Growth Depend on Exposure Time
Reproductive performance has been shown to be greatly affected by changes in environmental factors, such as temperature. However, it is also crucial to identify the particular stage of pregnancy that is most adversely affected by elevated ambient temperature. The aims of this study were to determine...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2012-01-01
|
| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/2012/359134 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832560635412480000 |
|---|---|
| author | Huda Yahia Hamid Md Zuki Abu Bakar Zakaria Goh Yong Meng Abd. Wahid Haron Noordin Mohamed Mustapha |
| author_facet | Huda Yahia Hamid Md Zuki Abu Bakar Zakaria Goh Yong Meng Abd. Wahid Haron Noordin Mohamed Mustapha |
| author_sort | Huda Yahia Hamid |
| collection | DOAJ |
| description | Reproductive performance has been shown to be greatly affected by changes in environmental factors, such as temperature. However, it is also crucial to identify the particular stage of pregnancy that is most adversely affected by elevated ambient temperature. The aims of this study were to determine the effect on reproductive outcomes of exposure to elevated ambient temperature during different stages of pregnancy and to determine the effect of prenatal heat stress on offspring growth. Sixty pregnant rats were used in this study. The rats were divided equally into four groups as group 1 (control), group 2 (exposed to elevated temperature following implantation), group 3 (exposed to elevated temperature during pre- and periimplantation), and group 4 (exposed to elevated temperature during pre- and periimplantation and following implantation). Groups 3 and 4 had prolonged gestation periods, reduced litter sizes, and male-biased sex ratios. Moreover, the growth patterns of group 3 and 4 pups were adversely affected by prenatal exposure to elevated temperature. The differences between group 1 and group 3 and between group 1 and group 4 were highly significant. However, no significant differences were observed between groups 1 and 2 in the gestation length, sex ratios, and growth patterns. Thus, it can be concluded that exposure to elevated ambient temperature during pre- and periimplantation has stronger adverse effects on reproductive outcomes and offspring growth than postimplantation exposure. |
| format | Article |
| id | doaj-art-e71a3b03df1a4ffa987e2237a7b1f70a |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-e71a3b03df1a4ffa987e2237a7b1f70a2025-02-03T01:27:09ZengWileyThe Scientific World Journal1537-744X2012-01-01201210.1100/2012/359134359134Effects of Elevated Ambient Temperature on Reproductive Outcomes and Offspring Growth Depend on Exposure TimeHuda Yahia Hamid0Md Zuki Abu Bakar Zakaria1Goh Yong Meng2Abd. Wahid Haron3Noordin Mohamed Mustapha4Department of Anatomy, Faculty of Veterinary Medicine, University of Khartoum, Khartoum 13314, SudanDepartment of Veterinary Preclinical Sciences, Faculty of Veterinary Medicine, Universiti Putra Malaysia, Selangor, 43400 Serdang, MalaysiaDepartment of Veterinary Preclinical Sciences, Faculty of Veterinary Medicine, Universiti Putra Malaysia, Selangor, 43400 Serdang, MalaysiaDepartment of Veterinary Clinical Studies, Faculty of Veterinary Medicine, Universiti Putra Malaysia, Selangor, 43400 Serdang, MalaysiaDepartment of Veterinary Pathology & Microbiology, Faculty of Veterinary Medicine, Universiti Putra Malaysia, Selangor, 43400 Serdang, MalaysiaReproductive performance has been shown to be greatly affected by changes in environmental factors, such as temperature. However, it is also crucial to identify the particular stage of pregnancy that is most adversely affected by elevated ambient temperature. The aims of this study were to determine the effect on reproductive outcomes of exposure to elevated ambient temperature during different stages of pregnancy and to determine the effect of prenatal heat stress on offspring growth. Sixty pregnant rats were used in this study. The rats were divided equally into four groups as group 1 (control), group 2 (exposed to elevated temperature following implantation), group 3 (exposed to elevated temperature during pre- and periimplantation), and group 4 (exposed to elevated temperature during pre- and periimplantation and following implantation). Groups 3 and 4 had prolonged gestation periods, reduced litter sizes, and male-biased sex ratios. Moreover, the growth patterns of group 3 and 4 pups were adversely affected by prenatal exposure to elevated temperature. The differences between group 1 and group 3 and between group 1 and group 4 were highly significant. However, no significant differences were observed between groups 1 and 2 in the gestation length, sex ratios, and growth patterns. Thus, it can be concluded that exposure to elevated ambient temperature during pre- and periimplantation has stronger adverse effects on reproductive outcomes and offspring growth than postimplantation exposure.http://dx.doi.org/10.1100/2012/359134 |
| spellingShingle | Huda Yahia Hamid Md Zuki Abu Bakar Zakaria Goh Yong Meng Abd. Wahid Haron Noordin Mohamed Mustapha Effects of Elevated Ambient Temperature on Reproductive Outcomes and Offspring Growth Depend on Exposure Time The Scientific World Journal |
| title | Effects of Elevated Ambient Temperature on Reproductive Outcomes and Offspring Growth Depend on Exposure Time |
| title_full | Effects of Elevated Ambient Temperature on Reproductive Outcomes and Offspring Growth Depend on Exposure Time |
| title_fullStr | Effects of Elevated Ambient Temperature on Reproductive Outcomes and Offspring Growth Depend on Exposure Time |
| title_full_unstemmed | Effects of Elevated Ambient Temperature on Reproductive Outcomes and Offspring Growth Depend on Exposure Time |
| title_short | Effects of Elevated Ambient Temperature on Reproductive Outcomes and Offspring Growth Depend on Exposure Time |
| title_sort | effects of elevated ambient temperature on reproductive outcomes and offspring growth depend on exposure time |
| url | http://dx.doi.org/10.1100/2012/359134 |
| work_keys_str_mv | AT hudayahiahamid effectsofelevatedambienttemperatureonreproductiveoutcomesandoffspringgrowthdependonexposuretime AT mdzukiabubakarzakaria effectsofelevatedambienttemperatureonreproductiveoutcomesandoffspringgrowthdependonexposuretime AT gohyongmeng effectsofelevatedambienttemperatureonreproductiveoutcomesandoffspringgrowthdependonexposuretime AT abdwahidharon effectsofelevatedambienttemperatureonreproductiveoutcomesandoffspringgrowthdependonexposuretime AT noordinmohamedmustapha effectsofelevatedambienttemperatureonreproductiveoutcomesandoffspringgrowthdependonexposuretime |