Immunological differences between monophasic and biphasic synovial sarcoma with implications for immunotherapy

Immunological differences between monophasic and biphasic synovial sarcoma with implications for immunotherapy

Abstract Synovial sarcoma is an aggressive soft-tissue cancer that shows limited responses to current immunotherapeutic approaches using immune checkpoint blockade or adoptive cell therapy. To improve immunotherapy for this cancer, understanding how the immune cells in the tumor microenvironment ass...

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Bibliographic Details
Main Authors: S. J. Luk, M. E. IJsselsteijn, A. Somarakis, I. Acem, I. Briaire de Bruijn, K. Szuhai, J. V. M. G. Bovee, N. F. C. C. de Miranda, J. H. F. Falkenburg, M. H. M. Heemskerk
Format: Article
Language:English
Published: Springer 2024-12-01
Series:Cancer Immunology, Immunotherapy
Subjects:
Synovial sarcoma
Sarcoma
Immunotherapy
T-cell therapy
Adoptive T-cell therapy
Survival
Online Access:https://doi.org/10.1007/s00262-024-03868-2
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