Advancing ex vivo functional whole-organ prostate gland model for regeneration and drug screening

Advancing ex vivo functional whole-organ prostate gland model for regeneration and drug screening

Abstract Model organisms are vital for biomedical research and drug testing but face high costs, complexity, and ethical issues. While newer techniques like organoids and assembloids have shown improvements, they still remain inadequate in addressing all research needs. In this study, we present a n...

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Bibliographic Details
Main Authors: Karthikeyan Subbiahanadar Chelladurai, Jackson Durairaj Selvan Christyraj, Kamarajan Rajagopalan, Johnson Retnaraj Samuel Selvan Christyraj
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Ex vivo whole organ model
Prostate gland
Regeneration
Drug screening
Valproic acid
Online Access:https://doi.org/10.1038/s41598-025-87039-y
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