Combined Effects of Estrogen and Mechanical Loading on Anterior Cruciate Ligament Fibroblast Biosynthesis

For some time, estrogen has been suspected to play a negative role in anterior cruciate ligament (ACL) fibroblast biosynthesis; however, reports on this issue have been controversial. In a recent study, our group demonstrated a negative combined effect of estrogen and mechanical loading on the gene...

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Main Authors: Xuhui Liu, Zong-Ping Luo
Format: Article
Language:English
Published: Wiley 2005-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2005.6
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author Xuhui Liu
Zong-Ping Luo
author_facet Xuhui Liu
Zong-Ping Luo
author_sort Xuhui Liu
collection DOAJ
description For some time, estrogen has been suspected to play a negative role in anterior cruciate ligament (ACL) fibroblast biosynthesis; however, reports on this issue have been controversial. In a recent study, our group demonstrated a negative combined effect of estrogen and mechanical loading on the gene expression of major extracellular matrix component molecules in ACL fibroblasts.
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institution Kabale University
issn 1537-744X
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series The Scientific World Journal
spelling doaj-art-e6edeea797cd46c1971d1d43f4e51e842025-02-03T06:05:52ZengWileyThe Scientific World Journal1537-744X2005-01-0155810.1100/tsw.2005.6Combined Effects of Estrogen and Mechanical Loading on Anterior Cruciate Ligament Fibroblast BiosynthesisXuhui Liu0Zong-Ping Luo1Sports Medicine Research Center, Department of Orthopedic Surgery, Baylor College of Medicine, 6550 Fannin Street, Suite 451, Houston, TX 77030, USASports Medicine Research Center, Department of Orthopedic Surgery, Baylor College of Medicine, 6550 Fannin Street, Suite 451, Houston, TX 77030, USAFor some time, estrogen has been suspected to play a negative role in anterior cruciate ligament (ACL) fibroblast biosynthesis; however, reports on this issue have been controversial. In a recent study, our group demonstrated a negative combined effect of estrogen and mechanical loading on the gene expression of major extracellular matrix component molecules in ACL fibroblasts.http://dx.doi.org/10.1100/tsw.2005.6
spellingShingle Xuhui Liu
Zong-Ping Luo
Combined Effects of Estrogen and Mechanical Loading on Anterior Cruciate Ligament Fibroblast Biosynthesis
The Scientific World Journal
title Combined Effects of Estrogen and Mechanical Loading on Anterior Cruciate Ligament Fibroblast Biosynthesis
title_full Combined Effects of Estrogen and Mechanical Loading on Anterior Cruciate Ligament Fibroblast Biosynthesis
title_fullStr Combined Effects of Estrogen and Mechanical Loading on Anterior Cruciate Ligament Fibroblast Biosynthesis
title_full_unstemmed Combined Effects of Estrogen and Mechanical Loading on Anterior Cruciate Ligament Fibroblast Biosynthesis
title_short Combined Effects of Estrogen and Mechanical Loading on Anterior Cruciate Ligament Fibroblast Biosynthesis
title_sort combined effects of estrogen and mechanical loading on anterior cruciate ligament fibroblast biosynthesis
url http://dx.doi.org/10.1100/tsw.2005.6
work_keys_str_mv AT xuhuiliu combinedeffectsofestrogenandmechanicalloadingonanteriorcruciateligamentfibroblastbiosynthesis
AT zongpingluo combinedeffectsofestrogenandmechanicalloadingonanteriorcruciateligamentfibroblastbiosynthesis