Association between maternal haemoglobin status during pregnancy and children’s mental and psychomotor development at 18 months of age: Evidence from rural Bangladesh
Background Anaemia is commonly caused by iron deficiency and screened by haemoglobin (Hb) concentration in blood. There is a scarcity of longitudinal data on the relationship between maternal Hb levels during pregnancy and neurodevelopment in children. Objective To measure the relationship of matern...
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Taylor & Francis Group
2024-12-01
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| Series: | Global Health Action |
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| Online Access: | http://dx.doi.org/10.1080/16549716.2024.2390269 |
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| author | Sayedur Rahman Lina Wallberg Anisur Rahman Eva-Charlotte Ekström Maria Kippler Jena D Hamadani Syed Moshfiqur Rahman |
| author_facet | Sayedur Rahman Lina Wallberg Anisur Rahman Eva-Charlotte Ekström Maria Kippler Jena D Hamadani Syed Moshfiqur Rahman |
| author_sort | Sayedur Rahman |
| collection | DOAJ |
| description | Background Anaemia is commonly caused by iron deficiency and screened by haemoglobin (Hb) concentration in blood. There is a scarcity of longitudinal data on the relationship between maternal Hb levels during pregnancy and neurodevelopment in children. Objective To measure the relationship of maternal Hb concentrations during pregnancy on early child development. Methods This prospective cohort study included 1,720 mother-child dyads in rural Bangladesh. Maternal Hb concentrations were measured at 14 and 30 weeks of gestation. The child’s Mental Developmental Index (MDI) and Psychomotor Developmental Index (PDI) at 18 months of age were measured using Bayley Scales of Infant and Toddler Development (BSID-II). Data on socio-demographic characteristics, anthropometrics, mothers’ IQ and children’s home stimulation were also collected. Bivariate and multivariable-adjusted linear regression analyses were used to explore associations of maternal Hb with child development. Results Mean Hb concentrations at 14 and 30 weeks of gestation were 116.6 g/L (±12.7) and 114.7 g/L (±12.7), respectively. Mean MDI and PDI scores among 18-month-old children were 78.9 (±12.4) and 93.8 (±13.7), respectively. Maternal 14-week Hb concentration was correlated with PDI (r = 0.06; p < 0.05) and 30-week Hb concentrations was correlated with MDI (r = 0.05; p < 0.05). Multivariable adjusted linear regression analysis showed that an increase in 14-week Hb concentrations increased the PDI scores among boys (β = 0.09; 95% CI: 0.02, 0.16). Hb concentrations at 30 weeks of gestation were not associated with MDI or PDI scores. Conclusion Higher maternal Hb concentrations at 14 weeks of gestation were associated with higher PDI among 18-month-old boys in Bangladesh. |
| format | Article |
| id | doaj-art-e6e4b19ff01f49708dee43e320954ebb |
| institution | Kabale University |
| issn | 1654-9880 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Global Health Action |
| spelling | doaj-art-e6e4b19ff01f49708dee43e320954ebb2025-02-05T12:46:14ZengTaylor & Francis GroupGlobal Health Action1654-98802024-12-0117110.1080/16549716.2024.23902692390269Association between maternal haemoglobin status during pregnancy and children’s mental and psychomotor development at 18 months of age: Evidence from rural BangladeshSayedur Rahman0Lina Wallberg1Anisur Rahman2Eva-Charlotte Ekström3Maria Kippler4Jena D Hamadani5Syed Moshfiqur Rahman6Uppsala UniversityUppsala UniversityInternational Centre for Diarrhoeal Disease ResearchUppsala UniversityKarolinska InstitutetInternational Centre for Diarrhoeal Disease ResearchUppsala UniversityBackground Anaemia is commonly caused by iron deficiency and screened by haemoglobin (Hb) concentration in blood. There is a scarcity of longitudinal data on the relationship between maternal Hb levels during pregnancy and neurodevelopment in children. Objective To measure the relationship of maternal Hb concentrations during pregnancy on early child development. Methods This prospective cohort study included 1,720 mother-child dyads in rural Bangladesh. Maternal Hb concentrations were measured at 14 and 30 weeks of gestation. The child’s Mental Developmental Index (MDI) and Psychomotor Developmental Index (PDI) at 18 months of age were measured using Bayley Scales of Infant and Toddler Development (BSID-II). Data on socio-demographic characteristics, anthropometrics, mothers’ IQ and children’s home stimulation were also collected. Bivariate and multivariable-adjusted linear regression analyses were used to explore associations of maternal Hb with child development. Results Mean Hb concentrations at 14 and 30 weeks of gestation were 116.6 g/L (±12.7) and 114.7 g/L (±12.7), respectively. Mean MDI and PDI scores among 18-month-old children were 78.9 (±12.4) and 93.8 (±13.7), respectively. Maternal 14-week Hb concentration was correlated with PDI (r = 0.06; p < 0.05) and 30-week Hb concentrations was correlated with MDI (r = 0.05; p < 0.05). Multivariable adjusted linear regression analysis showed that an increase in 14-week Hb concentrations increased the PDI scores among boys (β = 0.09; 95% CI: 0.02, 0.16). Hb concentrations at 30 weeks of gestation were not associated with MDI or PDI scores. Conclusion Higher maternal Hb concentrations at 14 weeks of gestation were associated with higher PDI among 18-month-old boys in Bangladesh.http://dx.doi.org/10.1080/16549716.2024.2390269bayley testhaemoglobinmental and psychomotor developmentchildrenbangladesh |
| spellingShingle | Sayedur Rahman Lina Wallberg Anisur Rahman Eva-Charlotte Ekström Maria Kippler Jena D Hamadani Syed Moshfiqur Rahman Association between maternal haemoglobin status during pregnancy and children’s mental and psychomotor development at 18 months of age: Evidence from rural Bangladesh Global Health Action bayley test haemoglobin mental and psychomotor development children bangladesh |
| title | Association between maternal haemoglobin status during pregnancy and children’s mental and psychomotor development at 18 months of age: Evidence from rural Bangladesh |
| title_full | Association between maternal haemoglobin status during pregnancy and children’s mental and psychomotor development at 18 months of age: Evidence from rural Bangladesh |
| title_fullStr | Association between maternal haemoglobin status during pregnancy and children’s mental and psychomotor development at 18 months of age: Evidence from rural Bangladesh |
| title_full_unstemmed | Association between maternal haemoglobin status during pregnancy and children’s mental and psychomotor development at 18 months of age: Evidence from rural Bangladesh |
| title_short | Association between maternal haemoglobin status during pregnancy and children’s mental and psychomotor development at 18 months of age: Evidence from rural Bangladesh |
| title_sort | association between maternal haemoglobin status during pregnancy and children s mental and psychomotor development at 18 months of age evidence from rural bangladesh |
| topic | bayley test haemoglobin mental and psychomotor development children bangladesh |
| url | http://dx.doi.org/10.1080/16549716.2024.2390269 |
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