Siponimod supports remyelination in the non-supportive environment
Abstract Inflammatory demyelination, a hallmark of multiple sclerosis (MS) lesions, leads to functional impairments and progressive axonal loss over time. Although remyelination is thought to protect axons, endogenous regenerative processes are often incomplete or fail entirely in many MS patients....
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Main Authors: | Johann Krüger, Newshan Behrangi, David Schliep, Leo Heinig, Elise Vankriekelsvenne, Nicole Wigger, Markus Kipp |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-02-01
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Series: | Scientific Reports |
Subjects: | |
Online Access: | https://doi.org/10.1038/s41598-025-87825-8 |
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