Coxsackievirus B3-Induced m<sup>6</sup>A Modification of RNA Enhances Viral Replication via Suppression of YTHDF-Mediated Stress Granule Formation

Coxsackievirus B3-Induced m<sup>6</sup>A Modification of RNA Enhances Viral Replication via Suppression of YTHDF-Mediated Stress Granule Formation

N6-methyladenosine (m<sup>6</sup>A) is the most prevalent internal RNA modification. Here, we demonstrate that coxsackievirus B3 (CVB3), a common causative agent of viral myocarditis, induces m<sup>6</sup>A modification primarily at the stop codon and 3′ untranslated regions...

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Bibliographic Details
Main Authors: Guangze Zhao, Huifang M. Zhang, Yankuan T. Chen, Kerry Shi, Sana Aghakeshmiri, Fione Yip, Honglin Luo, Bruce McManus, Decheng Yang
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Microorganisms
Subjects:
coxsackievirus B3
N6-methyladenosine
HuR
3D
reader protein YTHDFs
stress granule
Online Access:https://www.mdpi.com/2076-2607/12/11/2152
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